3C: Drug Delivery SIG 1: Smart Biomaterials for Therapy, Regeneration, and Sensing
Time: 8:00 AM to 10:00 AM
Description
This session will survey the diverse range of contemporary drug delivery systems and innovations. Drug delivering biomaterials can include nanoparticles, hydrogels, nanofibers, cell and virus-derived particles, or bioconjugates. Payloads can include DNA, RNA, antibodies, recombinant proteins, or small molecules. Disease applications can range from neurodegeneration to autoimmune disease, trauma, infection, or cancer. Work at all scales, from basic formulation science through therapeutic application in disease models is welcome. Studies that critically evaluate the impact of injection route on treatment efficacy and/or use novel imaging modalities to evaluate drug delivery performance are especially encouraged.
Moderators:
Dr. Aliasger Salem
Lyle and Sharon Bighley Endowed Chair & Professor / Associate Vice President for Research
University of Iowa, College of Pharmacy
John Martin
Assistant Professor
University of Cincinnati
Dr. Christine Wang
Assistant Professor of Materials Science and Engineering
Northwestern
8:00 AM. 114. Chemically modified RNA activated scaffolds enhance bone regeneration.Aliasger Salem, PhD1 1University of Iowa
8:15 AM. 115. Bone-targeted nanoparticles accelerate fracture healing in aged mice.Vigneshkumar Rangasami, PhD1, Danielle Benoit1 1University of Oregon
8:30 AM. 116. Hyaluronic Acid Microgels for Controlled Decorin Delivery To Reduce Upper Airway Fibrosis.Yashna Gupta1, Ryan Friedman, PhD1, Elizabeth Brown, MS2, Hannah Bonelli1, Matthew Aronson, PhD1, Kendra McDaid, BS, CVT, RLAT3, Karen Zur, MD3, Riccardo Gottardi, PhD1 1University of Pennsylvania, 2Stanford University, 3Children's Hospital of Philadelphia
8:45 AM. 117. Hydrogel-based approach for localized delivery of cardiac-specific gene therapy.Gabriella Kabboul, B.S.1, Luiza DaMotta, B.S.2, Lanfang Wang, M.S.3, Christopher Doering, PhD3, Andrés García, PhD2, Rebecca Levit, MD3 1Georgia Institute of Technology and Emory University, 2Georgia Institute of Technology, 3Emory University
9:00 AM. 118. Inflammation-responsive antibiotic coatings for prophylactic bacterial infection treatment in orthopedic reconstructions.Karina Bruce1, Dylan Marques1, Halle Tisovic1, Jacob Ryan1, Rais fataki1, David Wendell, PhD1, John Martin, PhD1 1University of Cincinnati
9:15 AM. 119. Super-Lubricious Platelet-Rich Plasma Loaded Microgels for the Treatment of Knee Osteoarthritis.Samuel Stealey, PhD1, Yousef Abu-amer, PhD2, Silviya Zustiak, PhD1 1Saint Louis University, 2Washington University in St. Louis
9:30 AM. 120. Nano-in-Microgel Combination Drug Delivery Platform for Localized Prolonged Immunomodulation to Prevent Allograft Rejection in Extrahepatic Islet Transplantation.Dhanashree Surve1, Chris Li2, Grisell Gonzalez3, Ana Hernandez3, Peter Buchwald4, Alice Tomei3 1University of Miami, 2Unviersity of Miami, 3University of Miami, Diabetes Research Institute, 4Diabetes Research Institute, University of Miami
9:45 AM. 121. Ingestible molecular probes for breath-based monitoring of microbiome drug metabolism.Vishal Manickam, BS1, Carly Kimpling, BS1, Khoi Le, BS1, Madeleine Troussé, BS1, Amy Kang, BS1, Aarsh Patel, BS1, Leslie Chan, PhD1 1Georgia Institute of Technology