3H: Immune Engineering SIG 1
Time: 8:00 AM to 10:00 AM
Description
Over the past decade the focus of many bioengineers and clinicians has been shifting towards "immune engineering" approaches that include but are not limited to engineered biomaterials for vaccines, immunotherapy (immune-modulation), cell and gene therapy, immune microenvironment engineering, and systems immunology. These research areas embrace a comprehensive list of translational immunology-associated problems including chronic infections, autoimmune diseases, aggressive cancers, allergies, etc. The purpose of the Immune Engineering SIG is to bring together emerging ideas and provide a venue for professional interaction to a large number of academic and industrial research groups and scientists working in these areas.
Moderators:
Michelle Teplensky
Assistant Professor of Biomedical Engineering
Boston University
Dr. Abhinav Acharya
Associate Chair for Research, Department of Biomedical Engineering
Case Western reserve University
8:00 AM. 153. Engineering the Immune Interface: A high-throughput platform for discovery of surface topographies that tune macrophage polarization in vitro and in vivo.Sudip Chakraborty1, Connor Edvall1, Pamela Allison Manco Urbina1, Adelmo Lopez2, Suman Bose, Ph.D.1 1Mayo Clinic, 2University of Michigan
8:15 AM. 154. Effects of Poly(β-amino ester) Networks on Macrophage Response In Vitro.Kayla Castillo-Aguilar, BS in Chemical Engineering1, Aiden Walter2, Stephanie Bryant, PhD3 1University of Colorado Boulder, 2Rose-Hulman Institute of Technology, 3Univeristy of Colorado - Boulder
8:30 AM. 155. CD45-Targeted IL-12 Drives a Multiepitope T Cell Response for Enhanced Lung Cancer Immunotherapy.Brett Pogostin, PhD1, Vidit Bhandarkar, PhD1, Olivia Sheridan, BS1, Sean-Luc Shanahan, BS1, Robert Langer2, Ana Jaklenec2, Darrell Irvine, PhD3, Stefani Spranger, PhD1 1MIT, 2Massachusetts Institute of Technology, 3Scripps Research Institute
8:45 AM. 156. Engineering Self-Therapeutic Nanoscale Hydrogels: Activity and Biodistribution Evaluation in Mice.John Clegg, PhD1, Mojtaba Ghanbari Mehrabani, MS1, Harsh Joshi, PhD1, Abigail Kauten1, Rana Ajeeb, PhD1 1University of Oklahoma
9:00 AM. 157. Modular Noncovalent Functionalization of Electrospun Piezoelectric Scaffolds with Bioactive Nanocarriers.Sarah Bortel, MS1, Sumayia Chowdhury, MS1, Jeremy Cheng, MS1, Daniella Uvaldo1, Mackenzie Wright1, Santiago Correa1, Treena Livingston Arinzeh, PhD1 1Columbia University
9:15 AM. 158. Systemically Administered Cd14 siRNA Lipid Nanoparticles Mitigate the Inflammatory Response to Intracortical Microelectrode Implants.Francine Graham, BSc1, Diarmuid Hutchinson, BSc1, Jeffrey Capadona, PhD2, Efstathios Karathanasis, PhD1 1Case Western Reserve University, 2Case Western Reserve University/Louis Stokes Cleveland Department of Veterans Affairs Medical Center
9:30 AM. 159. Mechanical Cues Shape Immunomodulation: Matrix Stress-Relaxation Modulates Macrophage Phenotype in 3D Brain-Mimicking Hydrogels.Audrey Jung, Undergraduate Student1, Mark Fleck, PhD Student1, Sauradeep Sinha, PhD2, Abena Peasah, PhD Student1, Fan Yang, PhD1 1Stanford University, 2St. Jude Children's Research Hospital
9:45 AM. 160. Smartphone-Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release.Alexander Bruckmann, M. S.1, Adam Goodman1, Mark Garren, Ph.D.1, Elizabeth Brisbois, Ph.D.1, Hitesh Handa, Ph.D.1 1University of Georgia