6E: Granular & Macroporous Biomaterials for Tissue Engineering 1
Time: 1:30 PM to 3:30 PM
Description
Granular hydrogel materials emerged as a class of biomaterial that provide for well-defined in vitro and in vivo systems with plug-and-play components and tissue-mimicking 3D environments. Granular hydrogels are composed of a slurry of microgel particles that are assembled to form a larger porous structure. Microporous annealed particle (MAP) scaffolds are a subclass of granular hydrogel material with a void space network stabilized by inter-particle chemical bonds. The modular nature of granular hydrogels offers enormous tunability in not only the individual microgel design but also the homogenous or heterogenous microgel assembly into the bulk scaffold. This session will explore current advances in granular hydrogel technology, including MAP scaffolds, for both immune modulation, tissue repair, organ-on-a-chip, and 3D-printing applications.
Moderators:
Tatiana Segura
Duke University
Donald Griffin
The University of Virginia
1:30 PM. 309. Talk by Chris Highley, Ph.D, University of Virginia
2:00 PM. 310. Affibody-Conjugated Hydrogel Microparticles for Affinity-Controlled Delivery of Angiogenic Proteins.Juan Garcia, BS1, Marian Hettiaratchi, Ph.D.2 1University of Oregon, 2University of Oregon Knight Campus
2:15 PM. 311. Varying Peptide Linkers to Modulate Degradation of Microporous Annealed Particle Scaffolds for Diabetic Wounds.Claudia Daboin1, Don Griffin, Ph.D.1 1University of Virginia
2:30 PM. 312. Modular control of hydrolytic degradation in microporous granular hydrogels guides skeletal muscle repair.Taimoor Qazi1, Zhiyuan Chen1, Tuba Marjan1, Nicole Mertens1 1Purdue University
3:00 PM. 314. Distinct Degradation Rates of MAP-AC and MAP-VS Hydrogels Modulate Healing Trajectories in Cutaneous Regeneration.Alejandra Suarez-Arnedo1, Amy Kim1, Tatiana Segura, PhD1 1Duke University
3:15 PM. 315. High-throughput buoyancy-clearing microgel production for simple user interfacing.Durante Pioche-Lee1, Sasha Cai Lesher-Pérez2 1Univeristy of Michigan, 2University of Michigan-- Ann Arbor