7G: Biomaterials for Neural Engineering 2
Time: 8:00 AM to 10:00 AM
Description
Engineered biomaterials are a centerpiece of new therapeutic approaches to treat neural injury as systems to deliver molecular and cell-based therapies to regenerate neural circuits or as components in closed-loop neurotechnologies. Biomaterials innovations that can improve the delivery of small molecules, biologics or cells to neural tissue, direct neuronal functional states, guide neural circuity connectivity, and improve neural cell interactions with devices hold the key to realizing new effective therapies. Furthermore, engineered biomaterials are uniquely positioned for use in creating, testing, and regenerating neural tissue with applications like in vitro models of injury and disease, brain organoid models, tissue engineering, therapeutic treatments, understanding neural development, and mapping the brain. This session will focus on cutting edge research in neural biomaterials including fundamental materials development work through pre-clinical and clinical studies. These include big questions surrounding understanding and treating neurological diseases and injuries of the peripheral and central nervous systems as well as drug, biologic, and cellular therapy delivery and neural interfacing. This session will be of significant interest to industry, academia, and clinical groups working in a broad array of neural engineering fields.
Moderators:
Michael Gower
Associate Professor | Affiliate faculty in Chemical Engineering
University of South Carolina
Timothy O'Shea
Assistant Professor (BME, MSE)
Boston College | College of Engineering
Kelly Langert, Ph.D
Assistant Professor
Molecular Pharmacology and Neuroscience
Loyola University Chicago, Stritch School of Medicine
8:00 AM. 388. Poly (Maltose - Lactate) Metabolic Copolymers Fuel Neural Progenitor Cell and Astrocytes Proliferation.Kunyu Li, master1, Timothy O'Shea, PhD1 1Boston University
8:30 AM. 390. Glycan Modified Biomaterials Support Neurogenesis After Ischemia Stroke.Sanchuan Che1 1Duke University
8:45 AM. 391. Monocyte Membrane Coated Nanoparticles Enable Active Targeting to Nerves in a Model of CMT1X.Harshita Kondeti1, Maleen Cabe, MS1, Kelly Langert, PhD1 1Loyola University Chicago
9:30 AM. 394. Activity Based Nanosensor to Interrogate Protease Activity by Cell Type, Region and Sex in Traumatic Brain Injury.Marianne Madias1, Jordan Nichols1, Ester Kwon1 1UCSD