7G: Biomaterials for Neural Engineering 2 

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: GH East AB

Description

Engineered biomaterials are a centerpiece of new therapeutic approaches to treat neural injury as systems to deliver molecular and cell-based therapies to regenerate neural circuits or as components in closed-loop neurotechnologies. Biomaterials innovations that can improve the delivery of small molecules, biologics or cells to neural tissue, direct neuronal functional states, guide neural circuity connectivity, and improve neural cell interactions with devices hold the key to realizing new effective therapies. Furthermore, engineered biomaterials are uniquely positioned for use in creating, testing, and regenerating neural tissue with applications like in vitro models of injury and disease, brain organoid models, tissue engineering, therapeutic treatments, understanding neural development, and mapping the brain. This session will focus on cutting edge research in neural biomaterials including fundamental materials development work through pre-clinical and clinical studies. These include big questions surrounding understanding and treating neurological diseases and injuries of the peripheral and central nervous systems as well as drug, biologic, and cellular therapy delivery and neural interfacing. This session will be of significant interest to industry, academia, and clinical groups working in a broad array of neural engineering fields.

Moderators:
Michael Gower
Associate Professor | Affiliate faculty in Chemical Engineering
University of South Carolina

Timothy O'Shea
Assistant Professor (BME, MSE)
Boston College | College of Engineering

Kelly Langert, Ph.D
Assistant Professor
Molecular Pharmacology and Neuroscience
Loyola University Chicago, Stritch School of Medicine

  • 8:00 AM. 388. Poly (Maltose - Lactate) Metabolic Copolymers Fuel Neural Progenitor Cell and Astrocytes Proliferation.Kunyu Li, master1, Timothy O'Shea, PhD1 1Boston University

  • 8:15 AM. 389. Off-target fibrotic effects of pro-angiogenic brain-reparative hydrogels and the role of microglia-pericyte crosstalk.Emma Whitehead, B.S.1, Tatiana Segura, PhD1, Katrina Wilson, PhD2, Kevin Erning, PhD3, Nicole Ratterman1 1Duke University, 2KBI BioPharma, 3Biomedical Engineering

  • 8:30 AM. 390. Glycan Modified Biomaterials Support Neurogenesis After Ischemia Stroke.Sanchuan Che1 1Duke University

  • 8:45 AM. 391. Monocyte Membrane Coated Nanoparticles Enable Active Targeting to Nerves in a Model of CMT1X.Harshita Kondeti1, Maleen Cabe, MS1, Kelly Langert, PhD1 1Loyola University Chicago

  • 9:00 AM. 392. A Hyaluronic Acid Hydrogel Multi-spheroid Midbrain Model for Studying Opioid Addiction.Ze Zhong Wang, Ph.D1, Zhan Shu, Ph.D2, Alexander Laperle, Ph.D3, Samantha Santacruz, Ph.D1, Clive Svendsen, Ph.D3, Nigel Maidment, Ph.D2, Stephanie Seidlits, PhD4 1University of Texas Austin, 2University of California, Los Angeles, 3Cedars-Sinai Medical Center, 4University of Texas at Austin

  • 9:15 AM. 393. Multifunctional platelet-like particles modulate inflammation and coagulation in polytrauma-traumatic brain injury.Diana Herrera-Diaz1, Luke Tucker, PhD2, Sierra Chimene, MS1, Amberlyn Simmons, MS1, Gregory Jensen, PhD1, Anastasia Sheridan-Muñana3, Sanika Pandit4, Crystal Willingham1, Ashley Brown, PhD5, Sarah Stabenfeldt, PhD1 1Arizona State University, 2North Carolina State University and The University of North Carolina at Chapel Hill, 3NC State University, 4NC State, 5North Carolina State University

  • 9:30 AM. 394. Activity Based Nanosensor to Interrogate Protease Activity by Cell Type, Region and Sex in Traumatic Brain Injury.Marianne Madias1, Jordan Nichols1, Ester Kwon1 1UCSD

  • 9:45 AM. 395. Engineering a long-lived human neurovascular PENTA culture to model vascular–neuroimmune remodeling after mild and moderate traumatic brain injury.Volha Liaudanskaya1, Daniel Hinrichsen1, Sunghyun Jun1, Sahan Kansakar2, Charitha Anamala1, Mitchell Thielen1 1University of Cincinnati, 2Unviersity of Cincinnati