Poster Presentations

Wednesday, March 25

POSTER SESSION I: BIOMATERIALS AFTER HOURS SOCIETY HANGOUT: CONNECT & DISCOVER
7:00 PM - 8:00 PM 

3D BIOPRINTING FOR DEVELOPING PERSONALIZED MODELS

PS1501. In-situ Bioprinting for Wound Healing: From On-Wound Constraints to Design Rules for Localized Bioactive Delivery (Mini-Review). Mahdi Arabinour1, Nargis Sultani2, Xiangyang Zhou1, Lobat Tayebi3 University of Miami, 2Georgia Institute of Technology, 3Old Dominion University

PS1502. Engineering a Hyaluronan-based Bioink for 3D printing of Cardiac-like Tissues. Shumaim Barooj, BTech1, Jaci Bliley, PhD2, Adam W. Feinberg, PhD2, Molly Shoichet, PhD1 1University of Toronto, 2Carnegie Mellon University

PS1503. Exploration of Pluronic F-127 as a 3D printed hydrogel. Andrew Chen1, Vladimir Reukov, Professor1, Niyal Patel1 1University of Georgia

PS1504. Cell-Laden Bioink for High-Fidelity 3D Bioprinting of Functional Hydrogels. Amreen Khan1, Sijil Chattopadhyay1, Rohit Srivastava1 1IIT Bombay

PS1505. Bioprinting Sodium Alginate-Gelatin Microtubular Structures using Low-Cost 3D Printer. Finnigan Poling, Graduate Student1 1Oklahoma State University

PS1506. Post-Print Reinforcement of GelMA+HAMA Scaffolds Via PEGDA Infiltration. Rishi Rajesh, Biochemistry BS1 1Southwestern University

PS1508. Microfluidic chip for the optimization of a vascularizing hydrogel to promote stem cell-derived islet vasculogenesis. Mariana Rodriguez, B.S. Candidate1, Angelica Torres1, Sophia Kioulaphides, B.S., M.S.1, Alexander Kedzierski, B.S., M.S.1, Ana Mora-Boza, PhD1, Andrés García, PhD1 1Georgia Institute of Technology

PS1509. Sundew-Inspired 4D Platform for Minimally Invasive Bone Cancer Therapy and Bioadhesive Regeneration. Jong Hwa Seo, B.S., Ph.D. Candidate1, Hoon Kim, Ph.D.2, Hyun-Do Jung, Ph.D.1 1Hanyang University, 2Graphy Inc.

PS1511. 3D Bioprinting of Cell-laden Electroactive Constructs for Enhanced Skeletal Muscle Restoration. Surendrasingh Sonaye1, Breanne Welsh1, Phuong TB Nguyen1, Derya Ozhava1, Chandra Khothapalli1, Prabaha Sikder1 1Cleveland State University

PS1512. PEG-Assisted 4D Printing of Porous Shape Memory Polymers for Physiological Actuation. Ebrahim Tajik1, Hossein Ravanbakhsh1, Pratima Poudel1 1University of Akron

PS1513. Engineering Acellular, Bioactive 3D-Printed Nipple–Areolar Complex Scaffolds to Promote Tissue Ingrowth and Vasculogenesis. Sahar Vakili, Ph.D.1, Alexandra Christensen2, John Fisher, Ph.D.2 1University of Maryland,College Park, 2University of Maryland

PS1514. Advanced Bio-fabrication: Bridging Current Innovations and Sustainable Future Directions. Libin Yang1, Kenan Song1 1University of Georgia

 

ADDITIVE MANUFACTURING OF PERMANENT POLYMER IMPLANTS

PS1515. Engineering 3D Printed Soft Tissue Implants with Sequential Proangiogenic Peptide Delivery. Alexandra Christensen1, John Fisher, Ph.D.1 1University of Maryland

PS1516. Modification of the physical and mechanical properties of PEEK processed with FFF additive technology for use in orthopedic implants. Wojciech Kajzer1, Gabriela Wielgus1, Jan Juszczyk1, Julia Lisoń-Kubica1, Ada Orłowska1, Aleksandra Kopica1, Anita Kajzer1 1Silesian University of Technology/Faculty of Biomedical Engineering

PS1517. 3D-Printed PCL Scaffolds with Multiscale Porosity Attained via Custom µPorous PCL–Sugar Porogen Filaments. Alan Shepardson, BS1, Mahshid Monavari, PhD1, Kamal Gautam, MS1, Yusuf Dikici, PhD1, Harihara Baskaran, PhD1, Ozan Akkus, PhD1 1Case Western Reserve University
 

ADVANCES FROM FORTUITOUS FAILURES

PS1518. Challenges in the Development of Gelatin Maleimide Microgels for Bone Marrow Engineering. Gunnar Thompson, PhD1, Brittany Payan, B.S.2, Brendan Harley3 1University of Illinois Urbana-Champaign, 2University of Illinois Urbana Champaign, 3University of Illinois at Urbana Champaign

 

ADVANCES IN DYNAMIC CROSSLINKING OF HYDROGELS

PS1519. Bioadhesive, Hybrid Hyaluronic Acid and Nanoparticle Hydrogels. Madisen Domayer1, Mukesh Gupta, Ph.D., Polymer Chemistry1, Craig Duvall, Ph.D., Biomedical Engineering1 1Vanderbilt University

PS1521. Mechanical Evaluation of a Dual Dynamically Covalently Crosslinked Hydrogel for Vascular Graft Regeneration. Rukhma Javaid1, Mohamed Abdelghafour1 1King Abdullah University of Science and Technology

PS1522. Development of 3D Printable Double Network Hydrogels With Tunable Mechanical Properties. Gokhan Kafes, Biomedical Engineer, MSc.1, Ozgul Gok, Assoc. Prof. Dr.1 1Mehmet Ali Aydınlar Acıbadem University

PS1523. Shear-thinning, injectable hydrogels for localized cell therapy. Alexander Osidach1, Abigail McSweeny1, Marcus Foley2, Nikhil Joshi2, Kara Spiller1, Christopher Rodell, Ph.D.1 1Drexel University, 2Cellular Vehicles

PS1524. Enhancing Osteogenesis by Controlling Spatio-temporal Cell-mediated Hydrogel Degradation. Yingjie Wu1, E. Thomas Pashuck1 1Lehigh University

PS1525. Photosoftening Macroporous Hydrogels for Engineering Soft Tissue. Golnaz Navidi1, Ben Canter1, Ella Morris1, Teresa Rapp, PhD1 1University of Oregon

PS1526. Entanglement-Driven Reinforcement in Dynamically Interpenetrated GelMA/PVA/Borax Hydrogels. Pritha Sarkar1, Amanda Bernard1, Kausik Mukhopadhyay, PhD1 1University of Central Florida

PS1527. Multiple-Step Ionic Coordination Using Zr-MOC Crosslinkers for Mechanically Robust Alginate Hydrogels. Tai-Lin Wu, B.S.1 1National Taiwan University

 

ANTIMICROBIAL AND ANTIBIOFILM BIOINTERFACES: STRATEGIES TO PREVENT DEVICE-ASSOCIATED INFECTIONS

PS1528. Water-soluble Peptidomimetic Polyurethanes Prevent Bacterial Biofilm Formation and Disrupt Preformed Biofilms. Zixi Chen1, Saba Nikjou1, Abraham Joy, N/A1 1Northeastern University

PS1529. An Advanced Surgical Irrigation Solution Utilizing Synergistic Technology Prevents Formation of Biofilms on Implantable Materials: An In vitro Study. Rebecca McMahon1, Nina Bionda, PhD2, Larry Estlack3 1Sanara Medtech, 2Rochal Technologies, R&D division of Sanara MedTech, 3Rochal Technologies (Sanara MedTech)

PS1531. Antibacterial Efficacy of Antibiotic-loaded Stimulan Beads Against Biofilms on Different Orthopedic Implant Surfaces. Tripti Gupta, PhD1, Nathan Sacaria1, Sean Aiken2, Phillip Laycock2, Daniel Wozniak, PhD1 1The Ohio State University, 2Biocomposites Ltd.

PS1532. A Microbial Spray Deposition System to Model Implant Contamination by Sedimentation of Aerosolized Contaminants. Amanda Hopster1, Olivia Swiber1, Nicole Gill2, Scott Korte1, Gaby Campos3, Gabriel Costa3, Nicolas Focarazzo3, Jennifer Gonzales-Pasion3, David Davies4, Lauren Destefano5, Jordan Katz5, Claudia Marques4, Thomas Schaer1 1University of Pennsylvania, 2Binghamton, 3Stevens, 4Binghamton University, 5Orthobond

PS1533. A Spray Deposition System to Model Bacterial Contamination in the Operating Room. Matthew Libera1 1Stevens Institute of Technology

PS1534. Nanostructured Polysaccharide-Based Coatings with In Situ Synthesized Silver Nanoparticles: Coating Stability and Antibacterial Activity. Alessandro Francisco Martins1, Rosecler Klein2, Paulo Souza2, Jenna Crouse3, Roberta Sabino3 1Pittsburg State University, 2State University of Maringa, 3University of Wyoming

PS1535. Platform for Peptoid Coarse-grained Simulation and Parameterization for Application in Tunable Antimicrobial Biomaterials. Xuyang Qin1, Yu Liu1, Shikha Nangia1 1Syracuse University

PS1536. Bioinspired phenol-based coatings against antimicrobial resistance. Daniel Ruiz Molina1 1ICN2-CSIC
 

BIOINSPIRED MATERIALS FOR THERAPEUTICS 

PS1537. The Connection between Sleeves in Active Sportswear and Therapeutic Medical Compression Garments. Hoorieeh Abbasi Mahmoodabadi1, Emiel DenHartog1, Minyoung Suh1, Martin King, PhD2 1North Carolina State University, 2NC State University

PS1538. Effect of Microneedle Design on Dermal Interstitial Fluid Extraction. Chizimuzo Chibuko1, Youseong Kim, PhD1, Isaree Pitaktong1, B. Pradeep Kumar Reddy, PhD1, Erkan Azizoglu, PhD1, Danial Hosseini, M.S.1, Mark Prausnitz, PhD1 1Georgia Institute of Technology

PS1539. Soft Matter Physics of Crowded Microgel Assemblies Enable Biomimetic Tissue Scaffolds. Andrew Lyon, PhD1, Daniel Cárdenas-Vásquez, PhD1, Elif Narbay, M.Eng.1, Abbygail Caine2, Marion Harper1, Neeraja Gajendran1, Marco Bisoffi, PhD1 1Chapman University, 2North Carolina State University

PS1540. Combinatorial Engineering of Substrate-Independent Superamphiphobic Coating Platform for Gasotransmitters. Natalie Crutchfield1, Anastasia Marx1, Divine J. Francis, Dr.2, Ekrem Özkan, Dr.3, Elizabeth Brisbois, Ph.D.1, Hitesh Handa, Ph.D.1 1University of Georgia, 2Harrell's LLC, 3spotLESS Materials

PS1541. Shear-Thinning Synthetic Polymer-Based Hydrogel Microparticles for Allogeneic Cell Delivery. Riyanka Narasimhan, B.A., Biochemistry and Chemical Biology (in progress)1, Mukesh Gupta, Ph.D., Polymer Chemistry1, Craig Duvall, Ph.D., Biomedical Engineering1 1Vanderbilt University    

PS1542. Strontium Doped Bioactive Glass Based 3D Printed Gels for Enhanced Cell Proliferation and Osteogenic Activity. Aasma Sapkota1, Ethan Renken1, Natalie Crutchfield1, Daniele Catori, PhD1, Elizabeth Brisbois, Ph.D.1, Hitesh Handa, Ph.D.1 1University of Georgia

PS1543. Rational Sequence Design Enables Scalable Recombinant Collagen with Preserved ECM-Mimetic Bioactivity. Qiang Hua, PhD, Biochemical Engineering1, Feng Liu, PhD, Biochemical Engineering2, Jie Zhou, PhD, Microbiology2, Amy Shi2 1East China University of Science and Technology, 2Jland Biotech

PS1544. Bone Morphogenetic Protein-2 Delivery from Hydroxyapatite-Binding Fusion Proteins for Enhancing Bone Allograft Efficacy. Malvika Singhal, BS1, Caroline Foskett2, Marian Hettiaratchi, Ph.D.3 1University of Oregon/Knight Campus, 2University of Oregon, 3University of Oregon Knight Campus

PS1545. Injectable Subcutaneous Depot of a Glucagon-like Peptide-1 Receptor Agonist Fused to Elastin-like Polypeptides as a Platform for Sustained Delivery. Rachel Strader1, Muskaan Iyer1, Ashutosh Chilkoti, PhD2 1Duke University, 2Duke

BIOINTERFACES SIG 

 

PS1546. Development of Hyaluronic Acid Thin Film Coatings for Enhancing Neural Probe Integration. David Frey1, Ander Switalla2, Jaisel Sappal3, Max Tenenbaum3, Felix Deku3, Marian Hettiaratchi, Ph.D.4 1University of Oregon, 2Phil & Penny Knight Campus for Accelerating Scientific Impact, Department of Bionengineering, 3Phil & Penny Knight Campus for Accelerating Scientific Impact, University of Oregon, 4University of Oregon Knight Campus

PS1547. Simultaneous Encapsulation and Seeding of Neural and Endothelial Cells in Alginate Hollow Microfibers. Nicole Hashemi1, Mychal Trznadel2, Lionel Ouedraogo2 1University of Missouri, 2Iowa State University

PS1548. Mechanical Cues Regulate Hormone-Induced Nascent ECM Deposition by Human Endometrial Stromal Cells. Grace Hinds, B.S.1, Arina Velieva1, Claudia Loebel, MD, PhD1 1University of Pennsylvania

PS1549. Characterizing Blood–Surface Interactions on Superhydrophobic Biomaterials for Enhanced Hemocompatibility. Thanh Phuong Hoang, Bachelor of Engineering with Honors1, Sina Naficy, PhD2, Sepehr Talebian, PhD2, Richard Tan, PhD1, Kieran Lau, PhD1, Chien Hung, PhD1, Jacopo Giaretta, PhD2, Matthew Crago, PhD1, Aeryne Lee, PhD1 1The University of Sydney, 2University of Sydney

PS1551. Peptide-Based Biointerfaces for Aggregation-Resistant Insulin Delivery Systems. Chinmaya Panda1, Sachin Kumar1, Sharad Gupta2, Lalit Mohan Pandey1 1Indian Institute of Technology Guwahati, 2Indian Institute of Technology Gandhinagar

PS1552. Antiplatelet Co-drug Delivery System Surface Coating for Improved Hemocompatibility on Nitric Oxide Releasing Medical Grade Polymer. Tia Shorter1, Anastasia Marx1, Elizabeth Brisbois, Ph.D.2, Hitesh Handa, Ph.D.2 1The University of Georgia, 2University of Georgia

PS1553. Engineered Air-Liquid Interface Culture Promotes Matrix Deposition by iPSC-derived Alveolar Type I Cells. Tara Tavakol, B.S.1, Claudia Loebel, MD, PhD1 1University of Pennsylvania

PS1554. Inducing dynamic vessel curvatures in engineered hydrogel channels via remote magnetic actuation. Emily Wang, BSE1, Claudia Loebel, MD, PhD1, Avinava Roy, M.S.E2 1University of Pennsylvania, 2University of Michigan

PS1556. One-Pot Construction of PEG–Alginate Double-Network Cryogels via Radical-Free Crosslinking for Load-Bearing Cartilage Tissue Engineering. Kaixiang Zhang1, Matthew Pinto1, Michael Seitz1, Era Jain, Ph.D.1 1Syracuse University

 

BIOMATERIAL-BASED THERAPIES FOR oSTEOARTHRITIS AND SKELETAL REPAIR 

PS1557. Preparation of Core-Shell Electrospun Fibers for Periodontal Tissue Regeneration. Saadman Alamgir1, A M U B Mahfuz1, Yuanyuan Duan1 1University of Mississippi Medical Center

PS1558. Cellular Uptake and Nuclear Localization of Biomimetic Proteoglycans. Annika Bergstrom, B.A. Biology1, Anita Li, PhD1, Sabrina Palumbo, B.S. Biology1, Efthimia Rukis, N/A1, Lin Han, PhD2, Michele Marcolongo, PhD, PE1 1VIllanova University, 2Drexel University

PS1559. Investigating the regenerative potential of osteoarthritis-patient derived chondrocytes using cartilage-mimetic hydrogels. Chun-Yi Chang, PhD1, Kristine Fischenich, PhD1, Karin Payne, PhD1, Stephanie Bryant, PhD2 1University of Colorado, 2Univeristy of Colorado - Boulder

PS1560. Cationic Polyamidoamine Dendrimers to Improve Hyaluronic Acid Treatment for Osteoarthritis. Madelyn Keller1, Simone Douglas-Green, Ph.D.1 1Georgia Institute of Technology & Emory University

PS1561. Organic acid-based anodization process to produce bioactive oxides on titanium implants. Arunendu Ettuthaiyil Sambasivan1, Amisha Parekh1, Amol Janorkar, PhD1, Michael Roach, PhD1 1University of Mississippi Medical Center

PS1562. Injectable and Piezoelectric Hydrogel for Osteoarthritis Therapy and Cartilage Regeneration. Gang Ge, Dr.1, I’jaaz Muhammad, Student1, Achal Duhoon, Student1, Thanh Nguyen, Ph.D.1 1University of Connecticut

PS1563. Bioengineered Ovarian Constructs to Maintain Bone Health in a Postmenopausal Rat Model. Kait Hosmer, Bach.1, Vivek Prakash, PhD2, Sittadjody Sivanandane, Bach.3, Marzieh Fattahi, MS4, Emmanuel Opara, PhD5, Justin Saul, PhD2, David Cohen, MD6, Zvi Schwartz, PhD, DMD6, Barbara Boyan, PhD6 1VCU, 2Miami University, 3Wake Forest Institute, 4University of Ohio, 5Wake Forest Institute for Regenerative Medicine, 6Virginia Commonwealth University

PS1564. Bioadhesion under shear flow on titanium materials. Nina Jazdzewski, 9128107021 1University of Kentucky

PS1565. Characterization of Super-Lubricious Copolymer Coated Hydrogel Microspheres for the Treatment of Knee Osteoarthritis. Hannah Johnson1, Samuel Stealey, PhD1, Maitreyi Bhagat1, Tarini Karnati1, Nathan Ly1, Paul Jelliss, PhD1, Silviya Zustiak, PhD1 1Saint Louis University

PS1566. Continuously graded TPMS (triply periodic minimal surface) scaffolds enable osteochondral defects repair through structural cues. Mirae Kim1, Evan Jones1, Cheng Sun1, Guillermo Ameer1 1Northwestern University

PS1567. Tissue Penetrating Hyaluronic Acid Hydrogel Protects Cartilage at Varying Simulated Stages of Degeneration. Christine Lee, B.S.1, Tristan Pepper, Ph.D.2, Jay Patel, Ph.D.3 1Georgia Institute of Technology, 2Georgia Institute of Technology and Emory University, 3Emory University

PS1568. Controlled Synthesis of Polysulfides to Generate Microparticles with Tunable ROS Reactivity. Patricia Poley1, Carlisle dejulius, Ph.D., Biomedical Engineering2, Craig Duvall, Ph.D., Biomedical Engineering1, Richard d'Arcy, Ph.D.3, Iris Cotoman1, Amelia Soltes1, Megan Keech1 1Vanderbilt University, 2ETH Zurich, 3Arizona State University

PS1569. Osteogenic and Inflammatory Responses to Titanium Implant Surfaces: Insights from In-vitro and In-vivo Models. Krishna Prajapati1, Anthony Reyes1, Bhuvana Lakkasetter Chandrashekar, PhD2, Jimena Mora1, Giulietta Peleg-Baldino, MS1, Medha Sundar Rajan, UG1, Estephania Garcia, UG2, Claudia Biguetti, DDS, MSc, PhD3, Danieli Rodrigues, PhD4 1The university of Texas at Dallas, 2The university of Texas at Rio Grande Valley, 3University of Texas at Rio Grande Valley, 4University of Texas at Dallas

PS1570. Bisphosphonates Loaded Nanoparticles in Microparticles: A Potential Immunomodulatory Macrophage Targeting and Intra-articular Sustained Delivery System for Osteoarthritis Therapy. Paul Sagoe1, Kaixiang Zhang1, Maddie Olson1, Zachary Varrenti2, Ramkumar Annamalai2, Era Jain, Ph.D.1 1Syracuse University, 2University at Buffalo

PS1571. Optimizing Design and Loading Parameters for Zirconia Compact Tension Testing. Riya Titus1, Kartikeya Singh Jodha2, Alvaro Della Bona3, Paula Benetti3, Michael Roach, PhD1, Susana Salazar Marocho1, Yuanyuan Duan1, Jeannette Simino1, Jason A. Griggs1 1University of Mississippi Medical Center, 2Loma Linda University, 3University of Passo Fundo

PS1572. Cementum-mimetic Titanium Nanosurfaces Induce Endogenous Periodontal Tissue Regeneration through Mechanotransduction. Masahiro Yamada, DDS, PhD1, Hiroshi Egusa, DDS, PhD, FRCPath2 1Tohoku University Graduate School of Biomedical Engineering, 2Tohoku University Graduate School of Dentistry
 

BIOMATERIAL-TISSUE INTERACTION SIG 

PS1573. Processing–Structure–Performance Design of Spray-Delivered Bioadhesives for Wound Repair: Review. Mahdi Arabinour1, Nargis Sultani2, Xiangyang Zhou1, Lobat Tayebi3 1University of Miami, 2Georgia Institute of Technology, 3Old Dominion University

PS1574. Development of a Tunable 3D Tissue Microenvironment Model to Investigate Angiogenesis in Bone Repair and Homeostasis. Delaney Marringa1, Alison Nunes2, Brendan Harley3 1University of Illinois Urbana-Champaign, 2University of Illinois at Urbana - Champaign, 3University of Illinois at Urbana Champaign

PS1575. Hydrolyzed Collagen Enhances Fibroblasts Migration and Proliferation: In Vitro Evidence. Sergio Medina1, Fahimeh Tabatabaei, PhD2, Nina Bionda, PhD2, Tiffany Sanchez2 1SANARA MEDTECH INC, 2Rochal Technologies, R&D division of Sanara MedTech

PS1576. Hydrolyzed Collagen Impacts Proliferation, Gene Expression, and Cytokine Production of Macrophages In Vitro. Fahimeh Tabatabaei, PhD1, Nina Bionda, PhD1 1Rochal Technologies, R&D division of Sanara MedTech

PS1577. Acoustic field enabled polymeric nanoparticle deposition onto vessel walls for enhanced drug delivery. Jianlei Wu, Master of Science1, Laura Bracaglia, PhD1 1Villanova University

PS1578. Development of Tissue Clearing Oligomers for Deep Observation of Live 3D Tissue Models by in situ Crosslinking. Masahiro Yagi, Bachelor1, Michiya Matsusaki, Ph.D.1 1The University of Osaka

 

BIOMATERIALS & SURFACES: FROM PIONEERING MEDICAL IMPLANTS TO ADVANCED THERAPIES

PS1579. Optimizing Elastin-like Polypeptide Chain Length for Tunable Bio-interfaces in Environmental and Biomedical Sensing. Olivia Bridges, BS1, Sheetal Chowdhury, BS1, Jared Cobb2, Amol Janorkar, PhD1 1University of Mississippi Medical Center, 2US Army Corps of Engineers

PS1580. Surface Functionalization of TiO₂ with Sustainable Biopolymers to Enhance Bioactivity. ANA PAULA GUERRA GOMES, ANA GOMES1, Jenna Crouse1, Roberta Sabino1 1UNIVERSITY OF WYOMING

PS1581. Long-Term Electrochemical Behavior of CoCrMo Implant Alloys during 24-Day immersion. Mohsen Karshenas, M.S.1, Amandine Impergre, Ph.D.1 1Clemson University

PS1582. Ensuring the Compressive and Flexural Strength After the Elution of 13-93B3 Borate Bioactive Glass from Poly (methyl methacrylate)-Based Bone Cement. William Kuenne, Bachelors of Science1, Rebekah Blatt, Bachelors of Science2, Richard Brow, PhD2, terence McIff, PhD1 1University of Kansas, 2University of Missouri Science and Technology

PS1583. Low-Temperature ALD-Based Surface Engineering of Ti-13Nb-13Zr Biomaterial. Julia Lisoń-Kubica1, Magdalena Antonowicz-Hüpsch1, Anna Taratuta1, Justyna Więcek- Chmielarz2, Karolina Wilk3, Julia Kolasa1, Bogusław Ziębowicz3, Roman Major2, Marcin Basiaga1 1Silesian University of Technology/Faculty of Biomedical Engineering, 2Polish Academy of Sciences, 3Silesian University of Technology

PS1584. Biofunctionalization of Sulfonated Polyetherketoneketone Pins with Gelatin–Gentamicin Coatings for Enhanced Biocompatibility and Antibacterial Activity. Madhulika Narayan, Post-graduate1 1IIT Bombay

PS1585. In Vitro Apatite-Forming Ability of Hydroxyapatite Whisker Reinforced Polyetheretherketone. Elizabeth O'Connell1, Luis Vega Lugo1, Zachary Roeder1, Ryan Roeder, PhD1 1University of Notre Dame

PS1586. Ar⁺ ion irradiation as a surface design tool to modulate immune cell behavior on silk fibroin. Viviana M. Posada1, Alexandru Marin2, Andrea Mesa-Restrepo2 1Pontificia Universidad Javeriana de Cali, 2Penn State

PS1587. Relating Adhesion Strength and Cell Metastasis via Laser Spallation. Austin Stallings1, Joy Resig1, Brandon Quigley1, Martha E. Grady, Ph.D. Theoretical and Applied Mechanics1 1University of Kentucky

PS1588. Optimizing Osteointegration: The Role of Calcium Phosphate Dual-Blasting in Implant Surface Texturing. Craig Rosenblum, M.S.1 1Himed LLC

PS1589. Pre-Stimulation of Murine Macrophages Increases Inflammatory Response to DAMPs In Vitro. Blayne Sarazin1, David Tran1, Stephanie Bryant, PhD2 1Univeristy of Colorado Boulder, 2Univeristy of Colorado - Boulder

PS1591. Tests of corrosion resistance of an Al2O3 coating applied to the surface of a Ti6Al4V alloy used in dental prosthetics. Witold Walke1, Piotr Pietrucha1, Barbara Rynkus1 1Silesian University of Technology

PS1592. Evaluation of degradation and biological properties of a polymeric coating for peri-implant infection prevention. Karolina Wilk1, Katarzyna Nowińska1, Joanna Jaworska2, Katarzyna Jelonek2, Roman Major2, Janusz Szewczenko1 1Silesian University of Technology, 2Polish Academy of Sciences

PS1593. 3D-Printed, Antioxidant Arteriovenous Grafts with SUrface Topography for Hemodialysis Access. Reyla Williams, M.Eng1, Yonghui Ding, Ph.D.1 1Worcester Polytechnic Institute

PS1594. A Drug-Loaded Flow Diverting Stent for Localized Delivery of Sunitinib to Intracranial Aneurysms. KAN WU, Ph.D1, malia McAvoy, M.D. M.S1, Kyung-hoon Kim, Ph.D.1, Buddy Ratner, Ph.D.1, Michael Levitt, M.D.1 1University of Washington

 

BIOMATERIALS AND NANOTECHNOLOGY FOR CANCER MODELING AND THERANOSTICS  

PS1595. Morphology Effect of PEGylated Iron Oxide Nanoparticles on the Enhancement of MRI Contrast Signal in Breast Cancer. Juan Beltran-Huarac1 1East Carolina unIVERSITY

PS1596. Assessing Drug Response and Invasion Patterns of Glioblastoma in Hyaluronic Acid Modified Hydrogels. Runing Cui1, Brendan Harley2 1University of Illinois Urbana-Champaign, 2University of Illinois at Urbana Champaign

PS1597. A Tissue Engineered Model of Bone Marrow Metastasis of Estrogen-Receptor Positive Breast Cancer. Prasiddha Guragain1, Hossein Tavana, PhD1 1The University of Akron

PS1599. The Role of Astrocytes and PDGFB-PDGFβ in Breast to Brain Cancer Metastasis. Paul Lee, BS1, Anna Kate Miedler1, Nathaniel Grabinski, BS1, Kyle Preusser, BS1, Jesse Reardon, BS1, Tabo Mkandawire1, Skylar Lynch, BS1, Gina Sizemore, BS, PhD1, Jessica Winter, BS, PhD1 1The Ohio State University

PS1600. Engineered biofunctional scaffolds modulate the in vivo tumor immune microenvironment. Kiyoon Min, PhD1, Susan Thomas, Ph.D.1 1Georgia Institute of Technology

PS1603. Integrated Effects of Mechanical and Biochemical Signaling on Breast Cancer Invasion. Anju Rana Magar, Research Assistant1, Hossein Tavana, PhD1 1The University of Akron

PS1604. Biomaterial-based three-dimensional osteosarcoma models reveal distinct stage-specific biological and therapeutic responses. Nikolaos Pipis, Ph.D.1, Sriya Sagi, MS1, Gisele Charpentier, B.S.1, Rameshwar Rao, MD PhD1 1Seattle Children's Research Institute

PS1605. Humidity-Driven Tunability of Electrospun Nanofiber Scaffolds for Tissue Engineering. Carter Rodzik1, Will Braun1, Alan Estrada1, Mary Bartelli2, Maggie Voice1, Victoria Santillan1, Smitha Rao1 1Michigan Technological University, 2Houghton High School

PS1606. Protein-Modified Hyaluronic Acid Hydrogels to Study Extracellular Matrix-Mediated Drug Resistance in Brain Metastatic Breast Cancer. Paromita Sarker1, Kendall Dornan2, Shreyas S Rao, Associate Professor1 1The University of Alabama, 2The Univeristy of Alabama

PS1607. Engineering a Precision Hydrogel-Organoid Model to Uncover Matrix-Driven Tumorigenesis. Esha Uddin, BS1, Daniel Garcia, BS, MA1, Noriyuki Nikiwashi, MD, PhD1, Joshua Liu, MS2, Claudia Loebel, MD, PhD2, Gordana Vunjak-Novakovic, PhD1, Ricardo Cruz-Acuna, PhD1 1Columbia University, 2University of Pennsylvania

PS1608. Engineered Hydrogel Platform Enables Novel Dual Therapy in Esophageal Adenocarcinoma. Daniel Garcia, BS, MA1 1Columbia University

PS1609. Matrix Mechanical Cue Regulates Glioblastoma Cell Phenotype in Engineered 3D Viscoelastic Microenvironments. Sadegh Ghorbani1, Michelle Huang1, Daiyao Zhang, BS1, Yueming Liu1, Christopher Long, BS1, Riley Marie Zwetsloot1, Esther Mozipo, BS1, Rameshwar Rao, MD PhD2, Annika Enejder1, Sarah Heilshorn, PhD1 1Stanford University, 2Seattle Children's Research Institute

PS1610. Crosstalk between epigenetic state and extracellular matrix signaling drives adaptive resistance to drugs in lymphoma. Shwetha Sridhar1, Ankur Singh, Dr.1 1Georgia Institute of Technology

 

BIOMATERIALS EDUCATION SIG 

PS1611. Equipping Undergraduate Researchers to Better Communicate Biomaterials Impacts. Karen Burg, Ph.D.1, Timothy Burg, Ph.D.1 1University of Georgia

PS1612. Engaging Students in Biomaterial Fundamentals and Engineering Design Through Soft Robotics. Holly Golecki, PhD1 1University of Illinois Urbana Champaign

PS1613. “Matter of Scale”: A Card Game Gamifying Size, Scale, & Material Science Concepts. Sean McDowell1, Ivonne Ivonne González-Gamboa1 1University of California San Diego

PS1614. Developing and Evaluating a Course-Based Undergraduate Research Experience in Biomanufacturing. Erika Shamaun1, Morgane Golan1, Cheryl Gomillion, Ph. D.1, Steven Stice, Ph.D.1 1University of Georgia

 

BIOMATERIALS FOR CELLULAR ENGINEERING

PS1510. A Vascularized Glioblastoma Tumor Spheroid Model for Studying Tumor Invasion and Therapeutic Response. Anagha Shreesha1, Sheridan Fok, PhD candidate2, Brendan Harley3 1University of Illinois at Urbana-Champaign, 2University of Illinois Urbana-Champaign, 3University of Illinois at Urbana Champaign

PS1615. Designing an Injectable, Antifibrotic Biomaterial Platform for Localized Delivery of Engineered Cells. Patrick Bednarz, Undergraduate1, Shalini Pandey, PhD1, Omid Veiseh, PhD1 1Rice University

PS1616. Effect of alginate microbead and nanoparticle systems on encapsulation efficiency and release of molecules. Joshua Bowlby1 1Wake Forest Institute for Regenerative Medicine

PS1617. Degradable Multiarm PEG Hydrogels with Tunable Stiffness and Diffusivity. Kristie Cheng1, Evelyn Lim1, Brett Stern, PhD2, Nicholas Peppas, ScD1, Janet Zoldan, PhD1 1University of Texas at Austin, 2UT Southwestern

PS1618. Chondrodifferentiation of Mesenchymal Stem Cells in bioactive Microporous Annealed Particle (MAP) scaffolds with immobilized BMP-6. Clare Flanagan1, Blaise Pfaff, PhD1, Don Griffin, Ph.D.1 1University of Virginia

PS1619. The Relevance of Phosphorylating Type-I Collagen Matrix and Its Tissue Regenerative Capabilities. Murugan Gunasekaran1 1Encoll Corp

PS1620. 3D Hydrogel-Based Platform for Systematic Assessment of Injection Parameters on Cell Therapy Outcomes. Raey Hunde1 1Georgia Institute of Technology

PS1621. Hydrogel Delivery of Thy-1 Helps Modulate Fibroblast Phenotype. Mathew Kibet1 1University Of Virginia

PS1622. Engineered bone marrow perivascular network (PVNs) for selective HSC expansion. Sohjeong Kim1, Brendan Harley2 1University of Illinois Urbana-Champaign, 2University of Illinois at Urbana Champaign

PS1623. Changes in Adhesion and Proliferation Rates of MC3T3 Preosteoblasts Cultured with Poly (methyl methacrylate)-Based Bone Cement. William Kuenne, Bachelors of Science1, Rebekah Blatt, Bachelors of Science2, Richard Brow, PhD2 1University of Kansas, 2University of Missouri Science and Technology

PS1624. Cellular Viscoelasticity Alterations Drive Malignant Mechano-Response in Colorectal Cancer. Astha Lamichhane, PhD1, Abhinav shenoy1, Shrinarayanee Rengarajan1, Audrey Head1, Oswin Zetino1, Aishah Jaffery1, Mykyta Kizilov1, Vsevolod Cheburkanov1, Vladislav Yakovlev, Professor1, Shreya Artha Raghavan, Associate Professor1 1texas a&m university

PS1625. Engineering Nanofibrous Hydrogels for Human Mesenchymal Stem Cell Manufacturing. Andres Roca-Arroyo1, Jhonatan Gutierrez-Rivera1, David Castilla-Casadiego, PhD1 1University of Miami

PS1626. Mechanisms behind fibrosis-resolving behavior of macrophages loaded with dexamethasone-releasing poly(lactic-co-glycolic acid) microparticles. Keerthana Srinivasan1, Tina Tylek, PhD1, Ezgi Dickson1, Kara Spiller1 1Drexel University

PS1627. Profiling the Secretome and Metabolome of Mesenchymal Stem Cells Cultured on Hydrogels with Varied Stiffness. Reesha Vayalakkara1, Joseph Corstvet1, Facundo Fernández1, Johnna Temenoff1 1Georgia Institute of Technolo

PS1628. Enhanced Barrier Function of a Tissue-Engineered Blood-Brain Barrier Model Fabricated with Decellularized Extracellular Matrix. Masaya Yamamoto, Ph.D.1, Yuji Zhao1, Naoto Washihira1, Sho Fujii, Ph.D.2, Tadao Tanabe, Ph.D.3, Tsuyoshi Kimura, Ph.D.4, Mako Kobayashi, Ph.D.1 1Tohoku University, 2Yamagata University, 3Shibaura Institute of Technology, 4Toyo University

PS1629. Synergistic Topographical and Electrical Cues Drive Rapid Three-Dimensional Myofiber Alignment and Functional Neuromuscular Junction Formation. Chun-Sheng YU1, Ying-Chieh Chen2 1National Tsing Hua University, 2National Tsing-Hua University

PS1630. Stress-induced Response of 3D Bioprinted Cell Filaments Under Controlled Strain Rates. Shanshan Zhang1, Yuan Lin1 1The University of Hong Kong

 

BIOMATERIALS FOR IMMUNE CELL THERAPY BIOMANUFACTURING 

PS1631. Synthetic Nanowire-Mediated Delivery of Genetic Material to Naive Human B Cells. Olivia Jones1, Zhonghai Dai1, Adya Verma1, Ankur Singh, Dr.1 1Georgia Institute of Technology

 

BIOMATERIALS FOR IMMUNOENGINEERING 

PS1632. Development of Avidity-Controlled Biotherapeutic Delivery Systems for the Treatment of Acute Kidney Injury. Arielle D'Elia1, Kenneth Kim2, Alleé Shaw, B.S.3, Sayeh Gholampoor, B.S.3, Jessica Friedrich, B.S.3, Akari Seiner, MS1, Alexander Osidach1, Carl Russell III, B.S.3, Abigail McSweeny1, Winni Gao, B.S.1, Danielle Soranno, MD3, Christopher Rodell, Ph.D.1 1Drexel University, 2Drexel University College of Medicine, 3Indiana University

PS1633. Engineered Nanowires Enable miRNA-Mediated Regulation of T Cell Exhaustion. Shaylyn Grier, BS Biomedical Engineering1, Rachel Ringquist, Ph.D1, Lucy Britto, BS1, Brian Woo1, Zhonghai Dai1, Ankur Singh, Dr.1 1Georgia Institute of Technology

PS1634. Chain Transfer Agent-Mediated Polymer Design for Dendritic Cell Maturation. Autumn Hengen, B.S.1, Samantha Singer, B.S.1, Arha Gandhi1, Marian Ackun-Farmmer, Ph.D.1 1Georgia Institute of Technology

PS1635. Co-Assembling Nanoscale Granules for Intracellular Delivery of  immunomodulatory Protein Therapeutics. Stephanie Herrera, BS MS1, Alex Adolphson1, Stephen Michel1, Gregory Hudalla1 1University of Florida

PS1636. Helminth-inspired supramolecular biomaterials to treat autoimmune disease. Ciana López, PhD1, Julia Williams1, Hanzi Zheng1, David Pisetsky, M.D., Ph.D.1, Joel Collier, PhD1 1Duke University

PS1637. Engineering a Biomaterial-Based Synergistic Enhancer System to Improve In Vivo Transduction of Non-Activated T Cells by Nipah-Pseudotyped Lentiviral Vectors. Lucas Olson, PhD1, Jingyu Zhao, MS1, Limei Shen, PhD1, Samuel Lai, PhD1 1UNC Chapel Hill

PS1638. Engineering Protein Nanosheets for Localized Protein Display in Solid Tumors. Ishmamul Hoque Sadab1, Yusef Haikal1, Raka Chakraborty1, Kate Kunst1, John Blazeck1, Julie Champion, PhD1 1Georgia Institute of Technology

PS1639. Microgel-Based Macrophage Metabolic Reprogramming for Inflammation Control and Tissue Regeneration. Yunqian Zhang1, Jennifer Simkin1, Ni Su1 1University of Kentucky

 

BIOMATERIALS FOR IN VITRO MODELS OF DISEASE 

PS1640. A novel human-sized 3D in vitro cervical dysplasia model for testing ethyl cellulose–ethanol ablation. Gatha Adhikari1, Alina Sharma1, Kaitlin Fogg, Dr.2, Jenna Mueller, Dr.1 1University of Maryland, 2Oregon State University

PS1641. Development of Magnesium Biomaterials for In Vitro Bone Models. Olayide Ashiru, Master's1 1JHU/APL

PS1642. Optimizing Osteogenic Differentiation of Mesenchymal Stem Cells on 3D Polymer-Ceramic Coated Scaffolds. Emma Kate Godin1, Sireen Faraz1, Weitong Chen, Ph.D.1, Timothy Burg, Ph.D.1, Karen Burg, Ph.D.1 1University of Georgia

PS1643. Dynamic Tissue-Engineered Model Reveals Early Insights into Diabetes-Induced Matrix Remodeling. Alexander Carter, MS1, Dan Simionescu, PhD1, Agneta Simionescu, PhD1 1Clemson University

PS1644. Modeling Acute Versus Chronic Wounds in Long Term 3D Fibroblast Culture in Microporous Annealed Particle Scaffolds. Claudia Daboin1, Don Griffin, Ph.D.1 1University of Virginia

PS1645. Advanced 3D Colorectal Cancer Models from ECM Biomaterial Development. Saeed Derakhshesh, PhD candidate1, Aleksander Skardal, PhD1 1The Ohio State University

PS1646. Bone Marrow Vascular Collagen Hydrogel for Sickle Cell Disease Modeling and Stem Cell Transplantation Studies. Arielle Efotte, M.S.1, Natasha Claxton, Ph.D.1, Mykel Green, Ph.D.1 1Tulane University

PS1647. Characterizing the Deformability and Adhesion of Epithelial Cell Monolayer. Sristi Gurung1, Yuan Lin1 1The University of Hong Kong

PS1648. Hyaluronic acid induces dormancy in brain metastatic triple-negative breast cancer cells in vitro. Elle Hellwarth1, Evan Ingmire1, Piper Larkin1, Shreyas S Rao, Associate Professor1 1The University of Alabama

PS1649. Dynamically Stiffening Silk-cECM Hydrogel System to Mimic Cardiac Fibrosis. Boeun Hwang, PhD1, David Kaplan1, Lauren Black, Ph.D.1 1Tufts University

PS1650. 3D Photopolymerizing Hydrogels for Natural Killer Cell Encapsulation. Rylee Newport1, Gabriella Flinn1, Sethumi Rajapakse1, Suzanne Lightsey1, Blanka Sharma, PhD1 1University of Florida

PS1651. Exploring Microgel-Based Drug Screening of Glioblastoma to Enable Personalized Therapies. Brittany Payan, B.S.1, Joel Kattoor2, Andrew Handzel1, Brendan Harley3 1University of Illinois Urbana Champaign, 2University of Illinois Urbana-Champaign, 3University of Illinois at Urbana Champaign

PS1652. Dual-Model Evaluation of N-acetylcysteine -Loaded Polymer Microparticles for Antioxidant Protection and Recovery in Neural Stem Cells. Nadeesani Sirinayake, PhD candidate1, Kyle Lampe, PhD1 1University of Virginia

PS1653. A Platform for High-Throughput Biomolecule Stimulation of Varied Cardiac Cell Syncytia Morphologies. Julia Vallier1, André Monteiro da Rocha2, Sasha Cai Lesher-Pérez3 1University of Michigan, Ann Arbor, 2University of Michigan, Ann Arbor Medical School, 3University of Michigan-- Ann Arbor

PS1654. Engineering Distensible Microscale Resistance Vessels. Victoria Vest1, Leon Bellan, PhD1, Cindy Ho1, Katherine Young1 1Vanderbilt University

PS1655. Cell Culture Inserts with Biodegradable Membranes for Advanced In Vitro Applications. Lindsay Woodard, PhD1, Lauren Costella, ME1 1Luna Labs USA

PS1656. Development of a hydrogel-based corneal scaffold with curvature using 3D-printed molds for corneal disease studies. Daxian Zha1, Hoyeol Kim1, Shaghaiegh Ebrahimi1, Makayla Roberts1, Kyu Shik Mun1, Mehrnoosh Saghizadeh1 1Cedars-Sinai Medical Center

PS1657. Dissecting Macrophage Secretome Effects on Stem Cell Bone Formation Using a 3D Microgel Model. Bodie Woodrum1, Yunqian Zhang1, Jay Patel1, Ni Su1 1University of Kentucky

BIOMATERIALS FOR ISLET CELL THERAPY - FROM INNOVATION TO COMMERCIALIZATION 

 

PS1658. High-Density Encapsulation of Insulin-Producing Beta Cells Within Microgel Building Blocks. Don Griffin, Ph.D.1, Juliana Bates1 1University of Virginia

PS1659. Engineering immunomodulatory and pro-angiogenic cells to prevent islet graft rejection. Cassidy Hart, MD1, Dilrasbonu Vohidova1, Alvaro Moreno Lozano1, Omid Veiseh, Ph.D.1 1Rice University

PS1660. Growth Factor-free Synthetic Hydrogel Enhances Marginal Corrective Dose of SC-Islets in the Gonadal Fat Pad of Diabetic Immune Deficient Mice. Sophia Kioulaphides, B.S., M.S.1, Angelica Torres1, Michael Hunckler, PhD1, Nathaniel Hogrebe, PhD2, Graham Barber, Research Technician1, Jeffrey Millman, Professor3, Esma Yolcu4, Haval Shirwan, Professor4, Andrés García, PhD1 1Georgia Institute of Technology, 2Washington University St. Louis, 3Washington University, St. Louis, 4University of Missouri

PS1661. In Vitro Model of the Confined Islet Transplant Site to Evaluate the Long-term Direct and Indirect Immune Protective Effects of Islet Biomaterial Encapsulation from Cytotoxic T Cells. Ilaria Pasolini, MS1, Ana Hernandez1, Sara Anderson2, Grisell Gonzalez1, Alice Tomei1 1University of Miami, Diabetes Research Institute, 2University of Miami

PS1662. Engineered Immunomodulatory Nanocarriers for Localized Tolerance Induction in Allogeneic Islet Transplantation. John-Paul A. Pham1, Chloe Filice1, Ava Stendahl2, Haval Shirwan, Professor3, Esma Yolcu3, Maria Coronel, PhD1 1University of Michigan, 2University of Michigan Medical School, 3University of Missouri

 

BIOMATERIALS FOR NEURAL ENGINEERING 

PS1663. Chitosan-based Injectable, Adhesive and Self-healing Hydrogels with Tunable Mechanical Properties for Nerve Regeneration. Cátia Correia1, Daniela Peixoto1, Diana da Costa1, Rui Reis1, Iva Pashkuleva1, Natália Alves1 1University of Minho

PS1664. Laminin-Derived Ile-Lys-Val-ala-Val (IKVAV) Gradients and PCL Nanofibers to Enhance Schwann Cell Migration. Alyana Ysabel Del Fierro1, Matthew Becker, PhD2, Cecila M. Motta3, Nicola Judge, PhD4, Rebecca Willits, PhD1 1Northeastern University, 2Duke University, 3University of Akron, 4Duke Univeristy

PS1665. Generation of iPSC-Derived BMECs through Developmentally Relevant WNT Signaling Using CRISPR Activation. Anna Ruth Madera1, Hannah Brien2, Daniel Chavarria, PhD2, Jonathan Brunger, PhD2, Ethan Lippmann, PhD2 1Mercer University, 2Vanderbilt University

PS1666. SILKBridge® Bionintegrative Nerve Guide: translational route of a silk-based electrospun/textile composite device from on-bench testing to first in human study. Elena Marcello1, Antonio Alessandrino1, Claudia Clavelli1, Valentina Vincoli1, Marco Biagiotti1, Giuliano Freddi1 1KLISBio srl

PS1667. Development of Peptide-Functionalized Gelatin Hydrogels to Support Maturation of iPSC-Derived Neurons. Nicole Marguerite1, Samirah Salifu1, Jamie Pouncey1, Phoebe Lin1, Ethan Lippmann, PhD1 1Vanderbilt University

PS1668. Bilayer Shape Memory Polymeric Nerve Conduits for Minimally Invasive Delivery. Pratima Poudel1, Ebrahim Tajik1, Hossein Ravanbakhsh1 1University of Akron

PS1669. Fabrication of Boldine Loaded PLLA  Nanofibers for Improved Neuroprotective Effect. ASHISH TRITAL1, Burhan Ates1, Ryan Gilbert1, Carlos Toro2, Sarah Fakher1 1Missouri University of Science and Technology, 2Mount Sinai

PS1670. Hydrogel Interfaces in Cerebral Organoid-on-a-Chip Models for Replicating Gray-White Matter Damage. Anthony Baker1, Natalie Smith2, Zane Lybrand, Ph.D.2, Michaelann Tartis, Ph.D.1 1New Mexico Institute of Mining and Technology, 2Texas Woman’s University

PS1672. Bioengineered models to probe membrane curvature sensing in oligodendrocytes. Eva Carvalho, PhD1, Madeline Cooper2, Luis A. Valencia3, Xingyuan Zhang3, Chongquan Huang4, Sing Y. Chew, PhD4, Bianxiao Cui3, J. Bradley Zuchero, PhD3 1School of Medicine Stanford University, 2Stanford University School of Medicine, 3Stanford University, 4Nanyang Technological University (NTU)

PS1673. Development of Mucoadhesive Nanoparticles for the Chronic Phase of Repeat Traumatic Brain Injuries. Nicholas Colonna, BS1, Michael Gower, PhD1, Maggie Davisson1 1University of South Carolina

PS1674. Development of polyacrylamide-methacrylated hyaluronic acid hydrogels to model in vitro CNS injury responses. Vasanti Dhakate1 1University of Akron

PS1675. Targeted Nerve Delivery of Stably Labeled Polymeric Nanoparticles Using Macrophage Plasma Membrane Coating. Chanpreet Kaur1, Maleen Cabe, MS2, Kelly Langert, PhD2, Kayla jordan1 1Loyola University Of Chicago, 2Loyola University Chicago

PS1676. Therapeutic efficacy of Intrathecal Rolipram-PgP treatment at 1 day post-injury in a rat moderate thoracic SCI model. Alex Vandenberg, BS1, Zhen Liao, PhD1, Adam Gatch, B.S.1, Namratha Appaji, BS1, Bradley Elliott, BS1, Ken Webb, PhD1, Megan Detloff, PhD2, Jeoung lee, PhD1 1Clemson University, 2Marion Murray Spinal Cord Research Center, Drexel University

PS1677. Synergistic Effects of Rolipram Loaded PgP and Minocycline on Motor Function and Secondary Injury in a Rat Moderate Controlled Cortical Impact TBI Model. Hee Chang Shin, M.S.1, Bradley Elliot, B.S.1, Alex Vandenberg, BS1, Namratha Appaji, B.S.1, Emanuel Ayala, M.S.2, Ken Webb, PhD1, Teresa Murray, PhD3, Jeoung lee, PhD1 1Clemson University, 2University of South Carolina, 3Louisiana Tech University

PS1679. Modulating Lipid-siRNA Conjugate Brain Distribution with a Cell-Targeted Peptide. Sarah Lyons1 1Vanderbilt University

PS1680. Elucidating the Role of Oligovascular Interactions in Shaping OPC Morphology. Samuel Agro, B.S.1, Kyle Lampe, PhD1, Lakeshia Taite, Ph.D.1, Joseph Maliakkal, Master of Technology1 1University of Virginia

PS1681. Quantifying Conformability of Dura Repair Products. Wagdi Mankarious1 1Depuy Synthes

PS1682. An Injectable Recombinant Polypeptide Scaffold for Peripheral Nerve Repair. Rachael Putman1, Maria Jantz, PhD2, Emily Song1, Daniel Joh, MD, PhD2, Warren Grill, PhD2, Neill Li, MD2, Stefan Roberts, PhD3, Ashutosh Chilkoti, PhD2 1Duke University, 2Duke, 3InSoma Bio

PS1683. Field-Deployable Topical Hydrogel for the Localized Treatment of Traumatic Brain Injury. Melissa Wright, ME1, Kate Johnson1, Catherine Sklar1, Ashley Hemp1, Rick Hassan, MS1, Lauren Costella, ME1 1Luna Labs USA

 

BIOMATERIALS FOR REGENERATIVE ENGINEERING 

PS1684. Base-Catalyzed Omega-3 Modification Enhances Hydrophobicity of Cellulose Microparticles. Benjamin Agyemang1, Andie Tubbs2 1The University of Memphis, 2University of Memphis

PS1685. Piezoelectric Biomimetic Scaffold Integrating Osteoinductive Cues. Nitu Bhaskar1, Zhiming Li1, Thanh Nguyen, Ph.D.1 1University of Connecticut

PS1686. In vitro assessment of crosslinker toxicity in lyophilized chitosan-based copolymer sponges for wound healing. Alex Bryan, MS1, Joel Bumgardner, PhD2, Antonin Broz, PhD3, Lucie Bacakova, PhD3 1The University of Memphis, 2University of Memphis, 3Institute of Physiology of the Czech Academy of Sciences

PS1687. Hydrogel-based Delivery of Antibacterial Agents Eliminate Staphylococcus aureus Infection and Heal Segmental Bone Defects. Eunice Chee, PhD1, Pranav Kalelkar, PhD1, Karen Martin, PhD1, Jeremy Caplin, Ph.D.1, Luiza DaMotta, B.S.1, Graham Barber, Research Technician1, Rebecca Schneider, PhD1, Nia Myrie1, Elisa Nieves1, Andrés García, PhD1 1Georgia Institute of Technology

PS1688. Endothelial and Mesenchymal Stem Cell Attachment and Proliferation on Porous Polycaprolactone Scaffolds for Bone Tissue Engineering. Clara Elliott1, Paola Aguirre1, Francisco Almaguer1, Marco Arriaga1, Hugo Brown1, Shainah Vidal1, Dean Michael Enriquez1, Sue Anne Chew, Ph.D.1 1University of Texas at Rio Grande Valley

PS1689. Modulating Bead Loading in an Oxygen-Generating 3D Printed Silicone Scaffold Alters Oxygen Generation. Cameron Crouse, B.S.1, Cherie Stabler, Ph.D.1, Jiapu Liang, Ph.D.2, Robert Accolla, Ph.D.3 1University of Florida, 2Samsung Biologics, 3Humacyte

PS1690. Preparation of Nanoparticle Fibrin Microfiber Sheets for Neuromuscular Repair. Dominic Davis1, Hai-Quan Mao, PhD1, Warren Grayson, PhD1 1Johns Hopkins University
 

Thursday, March 26

POSTER SESSION II: BIOMATERIALS AFTER HOURS SOCIETY HANGOUT: SCIENCE & SOCIAL HOUR
6:30 PM - 7:00 PM 

 

BIOMATERIALS FOR REGENERATIVE ENGINEERING 

PS2500. Hydrogen Sulfide-Releasing Bioresorbable Grafts for in Situ Remodeling in a Rat Carotid Artery Interposition Model. Xiaochu Ding1, Ying Grace Chen, Ph.D.2 1Michigan Technological University, 2Rowan University

PS2501.Development of Thiol-Ene Click Crosslinked Chitosan/Gelatin Hydrogels for Tissue Engineering. Joseph Duran1, Matthew Jungmann1, Krishna Patel1, Anu Anand1, Huy Bui1, Vansh Tandon1, Daniel Alge, PhD1 1Texas A&M University

PS2502. Immunomodulatory Effect of 3D Printed Silicon Carbide Orthopedic Device. Arash Ghalandarzadeh1, Ahmed El-Ghannam1, Didier Dreau1 1University of North Carolina at Charlotte

PS2503. Structure, Surface, and Thermal Properties of Electrospun PLA/Hydroxyapatite Scaffolds for Guided Bone Regeneration. Tomasz Gredes1, Andrii Lys2, Mykola Pavlenko2, Nikita Bobrov3, Igor Iatsunskyi3, Natalia Beshchasna4, Flavia Gonçalves5 1Technische Universität Dresden Medical Faculty, 2Adam Mickiewicz University, Poznań, 3Adam Mickiewicz University in Poznan, 4Fraunhofer Institute for Ceramic Technologies and Systems IKTS, 5Universidade Santo Amaro (UNISA)

PS2504. Pore size influences myogenesis in microporous annealed particle (MAP) scaffolds. Annabelle Hendrickson, B.A.1, Don Griffin, Ph.D.1, Steven Caliari, Ph.D.1 1University of Virginia

PS2505. Growth Factors and Enhancers for Craniofacial, Dental, Periodontal and Oral Surgical Regeneration of Hard Tissue. Robert Horowitz, DDS1 1NYU College of Dentistry

PS2506. Non-invasive methods for increasing vital bone in grafted dento alveolar, other bony sites. Robert Horowitz, DDS1 1NYU College of Dentistry

PS2507. Biomimetic Limited Basement Membrane Proteolysis of Xenogeneic Pericardium Extracellular Matrix Modulates Mesenchymal Stem Cell Migration and Preserves Endothelial Quiescence. Kamal Hussein, DVM, PhD1, Likitha Somasekhar1, Isadora Guarino, MD1, Leigh Griffiths, VetMB, MRCVS, PhD.1 1Mayo Clinic, Rochester

PS2508. Sustainable Low-Dose Hydrogen Peroxide Release from Glucose Oxidase-Loaded Gelatin-Hydroxyphenyl Propionic Acid Coated Plates Attenuate Cellular Senescence. Hyeonjun Hwang1, Hye-min Park1, Minseo Park1, Ki Dong Park1, Hyun-Ji Park1 1Ajou university

PS2509. A Multifunctional Graphene Oxide– Polydeoxyribonucleotide  Hydrogel with Optimized Antioxidant and Regenerative Functions for Diabetic Wound Healing. Se-Jin Choi1, Min-Ho Kang1 1The Catholic University of Korea

PS2510. Assessment of proinflammatory activity in post-processed decellularized ECMs using IL-1β-HiBiT–Tagged THP-1 cells. Tsuyoshi Kimura, Ph.D.1, Mika Suzuki1, Wataru Nomura2, Sumio Ohtsuki3, Akio Kishida4 1Toyo University, 2Hiroshima Univ., 3Kumamoto University, 4Institute of Science Tokyo

PS2511. Hybrid ROS-responsive Nanoparticle and Gelatin Hydrogels for Stem Cell Delivery to Diabetic Skin Wounds. Anna Kittel1, Mariah Bezold1, Fang Yu, MD, PhD1, Mukesh Gupta, Ph.D., Polymer Chemistry1, Craig Duvall, Ph.D., Biomedical Engineering1 1Vanderbilt University

PS2512. 3D Printed Self-Powered Piezoelectric Smart Scaffolds for Enhanced Bone Tissue Regeneration. Zhiming Li1, Nitu Bhaskar1, Thanh Nguyen, Ph.D.1 1University of Connecticut

PS2513. Characterization and Mineralization of PHB/SF Electrospun Scaffolds for Tendon. Milenka Men1, Amritha Anup1, Mika Bok1, Katelyn Wasacz1, Katherine Hixon1 1Dartmouth College

PS2514. Dynamic Aqueous Partitioning Within Collagen:Microgel Biocomposites. Elif Narbay, M.Eng1, Andrew Lyon, PhD1, Marion Harper1 1Chapman University

PS2515. Differentiation of Human Dental Pulp Stem Cells to Neuron-Like Cells in 3D Hydrogel Cultures for Neurodegenerative Diseases. Aya Naser1, Sofia Bufano1, Marie Elizabeth Georgescu1, Ellison Fleming1, Madison Sexton1, Congyue Annie Peng1 1Clemson University

PS2516. Facile Synthesis of Poly(ethylene glycol)-Polyurethane Hydrogels for Tissue Engineering Applications. Ashley Onumonu1, Harkiran Singh1, Tianna James2, Lakeshia Taite, Ph.D.1 1University of Virginia, 2North Carolina A&T State University

PS2517. Addressing Batch Consistency and Scalability Challenges in Functionalized Natural Polymers Manufacturing. GANGADHAR PANAMBUR, PhD1, Trevor Bos1, Emma Hainstock1, Adam Raw, PhD1 1MilliporeSigma

PS2518. Hyaluronic Acid (HA) Binding Peptide Functionalized PLGA/PCL Core-Shell Nanofibers with Tunable Degradation for Endogenous HA-enriched Regenerative Wound Dressings. Whitney Ponwith1, Tugba Ozdemir1 1South Dakota Mines

PS2519. Bulk RNAseq Evaluation of Cx43 Overexpression on Bone Mesenchymal Stem Cells Utilizing a Lentiviral Delivery System Reveals Activation of BMP and TNFα Pathways. Ingrid Rosko1, David Kohn1 1University of Michigan

PS2521. Multifunctional 3D-Printed Hydrogel Scaffold for Post-Surgical Osteosarcoma Ablation and Bone Regeneration. Jong Hwa Seo, B.S., Ph.D. Candidate1, Hyun-Do Jung, Ph.D.1, Seojoon Bang, M.S., Ph.D. Candidate1 1Hanyang University

PS2522. Freeze-dried Macroporous Microparticles as Injectable Cell Scaffolds for Regenerative Medicine. Quintin Spey, BS, MS1, Leonor Teles, BS1, Alice Tomei2 1University of Miami, 2University of Miami, Diabetes Research Institute

PS2523. Senescence-Modulating Cryogel Scaffolds for Enhanced Osteogenesis Following Radiation Therapy. Peter Bertone1, Levi Olevsky1, Katherine Hixon1, Chelsea Bahney2, Maria Eduarda Torres Gouveia1 1Dartmouth College, 2University of California San Francisco

PS2524. Noninvasive Monitoring of Photocrosslinked Hydrogel Degradation with Methacrylate-Modified Gold Nanoparticles: Effects of Methacrylate Ligand Density. Hezekiah Williams1, Nick Adams1, Lara Celebi1, Lan Li, PhD1, Ryan Roeder, PhD1 1University of Notre Dame

PS2525. Injectable Cell-Laden Hydrogels Enables In Utero Regeneration of Cleft Palate in a Ovine Model. He Xia1, Elizabeth Reynolds1, Han Jin1, Christopher Pivetti1, Taylor Tran1, Granger Wong1, Diana Farmer1, Aijun Wang1 1University of California, Davis

PS2526. Enhancing Biocompatible Citrate-Based Polymer Films via Chitosan Integration for Tissue Suturing Applications. Nataraja Yadavalli, Ph.D.1, Bayabya Joshi1, Neeti Gandhi, Ph.D.2, Matthew Bury2, Amarin Sharma2, Arun Sharma, Ph.D.2, Breeanna Urbanowicz, Ph.D.1 1University of Georgia, 2Ann & Robert H. Lurie Children’s Hospital of Chicago

 

BRIDGING SCIENCE AND MARKET: COMMERCIAL PATHWAYS FOR BIOMATERIALS 

PS2528. Laser Fabrication and Mechanical Evaluation of Polyester and Polypropylene Barbed Sutures. Marziyeh Boosaliki, PhD student1, Karuna Nambi Gowri, PhD2, Walid Al Asad3, Adam Summers, MD4, Xin Zhao, PhD3, Martin King, PhD5 1Wilson College of Textile North Carolina State University, 2Wilson College of Textiles, North Carolina State University, 3Clemson University, 4The Aesthetic Institute, 5NC State University

PS2529. Development of Reproducible Tools for Uniform Wound Creation in In Vitro and Ex Vivo Models. Mojtaba Javid1, Fahimeh Tabatabaei, PhD2 1CLYTE Technologies, 2Rochal Technologies, R&D division of Sanara MedTech

PS2530. Laser Scanning Confocal Microscopy for Detecting Residual Machining Oils on Metallic Medical Device Components. Gopinath Mani, PhD1, Corey LaSalle, Senior Scientist1, Molly Gjerde, Engineer1, Sarah Hankins, Manager1, Dori Chretin, Principal Scientist1, Andreas Ornberg, Director1, Scott Citrowske, Senior Manager1, Robert Shulfer, Director1, Marika Kamberi, PhD1 1Abbott

PS2531. Extending SEM Utility: Qualitative Detection of Machining Oil Residues on Metallic Biomaterials. Gopinath Mani, PhD1, Corey LaSalle, Senior Scientist1, Molly Gjerde, Engineer1, Sarah Hankins, Manager1, Dori Chretin, Principal Scientist1, Andreas Ornberg, Director1, Scott Citrowske, Senior Manager1, Robert Shulfer, Director1, Marika Kamberi, PhD1 1Abbott

PS2532. Development of an FTIR-Based Method for the Detection of Machining Oil Residues on Metallic Biomaterial Surfaces. Gopinath Mani, PhD1, Corey LaSalle, Senior Scientist1, Molly Gjerde, Engineer1, Sarah Hankins, Manager1, Dori Chretin, Principal Scientist1, Andreas Ornberg, Director1, Scott Citrowske, Senior Manager1, Robert Shulfer, Director1, Marika Kamberi, PhD1 1Abbott

PS2533. Biodegradable Medical SuperGlue of α-Lipoic Acid for Soft Tissue Repair. Subhajit Pal, PhD1, Phillip Messersmith, PhD1 1UC Berkeley

 

COMPUTATIONAL, MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE APPROACHES TO BIOMATERIALS 

PS2534. Automation and Machine Learning for Self-Driving Antibody Formulation. Cristian Lopez1, Adam Gormley, Ph.D.2, D. Christopher Radford1, Elena Di Mare1 1Rutgers University, 2Rutgers University, New Brunswick

 

DESIGNING BIOMATERIALS FOR USE AS BIO-INKS

PS2535. Thermally Tuned Magnesium Phosphate Bioceramics and 3D Printed Scaffolds for Advanced Biomedical Applications. Reedwan Auniq, M.S.1, Salil Desai, Ph.D.1, Narayan Bhattarai, PhD2 1North Carolina A&T State University, 2NCAT

PS2536. Microwave-Assisted Synthesis of Gelatin-Norbornene for High Fidelity Bioprinting. Jonathan Bryan, M.S.1, Chien-Chi Lin, PhD2 1Purdue Univerisity, 2Purdue University

PS2537. FRESH 3D Bioprinting of Human Induced Pluripotent Stem Cell-derived Hepatocytes (iHeps) Using Fibrin and Hyaluronic Acid Bioinks. Margaret Cruz1, Ali Adib, PhD1, Rodrigo Florentino, PhD2, Lanuza Faccioli, PhD2, Sam Moss, PhD1, Daniel Ranke1, Alicia Chua1, Prakruti Vora1, Alejandro Soto-Gutierrez, MD, PhD2, Adam Feinberg, PhD1 1Carnegie Mellon University, 2University of Pittsburgh

PS2538. Coaxial Microfluidic Bioprinting of Hyaluronan-Alginate Interpenetrating Networks for Tailored Epithelia-Mesenchyme Layering in Salivary Gland Tissue Engineering. Ephraim Vazquez-Rosado1, Yu Yin, PhD1, Daniel Harrington, PhD1 1The University of Texas Health Science Center at Houston

PS2539. Evaluating the effects of poly(ε-caprolactone)-hydroxyapatite composite ink composition on 3D printed scaffold structural properties. Maeve Kennedy1, Vasiliki Kolliopoulos1, Konstantinos Loukelis1, Andrew Goin1, Luis Diaz-Gomez2, Elias Sikavitsas1, Udayabhanu Jammalamadaka1, Ellena Jeon1, Felix Wang1, Varun Gunda1, Antonios Mikos1 1Rice University, 2Universidad de Santiago de Compostel

PS2540. 3D Printed N-MAC Chitosan-PEGDMA Hydrogels with Magnetic Collagen Fibers for Volumetric Muscle Loss. Nikken Malboeuf, B.S1, Antonin Broz, PhD2, Joel Bumgardner, PhD1, Tomoko Fujiwara, PhD1 1University Of Memphis, 2Institute of Physiology of the Czech Academy of Sciences

PS2541. Development of a Multifunctional Hyaluronic Acid Methacrylate Hydrogel Incorporating MXene and Salmon-Derived DNA for Osteosarcoma Treatment. Hyeong Seok Kang, B.S. Candidate1, Chan Ho Moon, B.S. Candidate1, Hyun-Do Jung, Ph.D.1 1Hanyang University

PS2542. NIR-Responsive 3D-Printed Liquid Metal Gallium Scaffold for Post-Surgical Cancer Therapy and Skin Regeneration. Jong Hwa Seo, B.S., Ph.D. Candidate1, Hyun-Do Jung, Ph.D.1 1Hanyang University

PS2543. Thiol-ene modification of a recombinant collagen-like protein as photocurable bioink. Sven Weber, PhD1, Ryan Heniford, M.S.1, Chander chawla, PhD, MBA1 1Evonik

PS2544. Multiscale Engineered Heterogeneous Hydrogel Composites for Digital Light Processing 3D Printing. Yuang Zhang1, Ryan Davis Jr.1, Saptarshi Biswas1, Sarah Miller1, Syed Raza Ur Rehman1, Gene Felix1, Akhilesh Gaharwar1 1Texas A&M University

 

DRUG DELIVERY SIG 

PS2545. Biodegradable, Cationic Nanogels for the Multi-Responsive Delivery of Therapeutics to Treat Neuroinflammation. Rachel Aguillard1, Nicholas Peppas, ScD2 1The University of Texas at Austin, 2University of Texas at Austin

PS2546. High-Throughput Approach for Evaluating the Solubility of Polymer-Stabilized Proteins in Organic Solvent. Eman Ahmed1, Adam Gormley, Ph.D.1 1Rutgers University, New Brunswic

PS2547. Mitochondrial-Targeted Dendrimer Platform for Precision Hepatocellular Carcinoma Therapy. Ananya Biswas1, Vikrantvir Jain1, Aqib Iqbal Dar1, Anjali Sharma1 1Washington State University

PS2548. Sodium Thiosulfate Nanoparticles Shield Sensory Hair Cells against Cisplatin in Preclinical 3D Cochlear Culture and Zebrafish. Brototi Chakrabarty, Student1, Neeraj Thakur, Student1, Marisa Zallocchi, Assistant Professor2, Vibhuti Agrahari, Ph.D.3 1University of oklahoma health science center, 2Creighton University, 3University of Oklahoma Health Campus

PS2549. Mucosa-targeted Inflammatory Bowel Disease Therapeutics for Localized Intestinal Immunosuppression. Jaibyung Choi, MS1, Anna Davis, BS1, Ayowole Akinsola1, Paul Dawson, PhD2, Leslie Chan, PhD1 1Georgia Institute of Technology, 2Emory University

PS2550. Sequence-Guided Design of Antioxidant Self-Assembling Peptides with Tunable Supramolecular Properties for Drug Delivery. Jun Shik Choi, Ph.D.1, Woo Hyun Kwon, Mr.1, Sang Jun Park, Ph.D.1, Woo-jin Jeong, Ph.D.2, Ilkoo Noh, Ph.D.3, Chun Ho Kim, Ph.D.1 1Korea Institute of Radiological & Medical Sciences (KIRAMS), 2Inha University, 3Kangwon National University

PS2551. Rapamycin-loaded uPA-mediated Dendrimer Nanoparticles for Inflammation Modulation and Plaque Stabilization in Atherosclerosis. Hsin-Yin Chuang1, Huari Kou1, Yue-Wern Huang1, Hu Yang2 1Missouri University of Science and Technology, 2Marquette University and Medical College of Wisconsin

PS2552. Synthesis and Evaluation of Pt(IV) Prodrugs for Improved Efficacy and Reduced Systemic Toxicity. Karla Cisneros1, Samantha Hall, M.S.2, Timothy Brewster, PhD1, Joel Bumgardner, PhD1, Tomoko Fujiwara, PhD1 1University of Memphis, 2The University of Memphis

PS2553. Assessing Combination Therapy Effectiveness Against Glioblastoma Using Surfen-Loaded PLGA Microparticles with Temozolomide and Radiation. Amin Davarzani, M.Sc.1, Md Marzan Sarkar, M.Sc.1, Gee Young Lee, Ph.D.2, Tyler Windfield Judd2, Leidong Mao, Ph.D.1, Renee Read, Ph.D.2, Lohitash Karumbaiah, Ph.D.1 1University of Georgia, 2Emory University

PS2554. Development, characterization, and quantification of Curcumin by HPLC in Poly lactic-co-glycolic acid (PLGA) nanoparticles with various Lactic/Glycolic Acid ratios for skin Melanoma Therapy. Amit Dey, Ph.D. in progress1, Mishal Pokharel, Ph.D.1, Kosar Fateh, Ph.D. in progress1, Emma Thiboutot, Undergraduate Student1, Shupti Shaha, Ph.D. in progress1, Tracie Ferreira, Professor1 1University of Massachusetts Dartmouth

PS2555. Peptide-mediated delivery of mRNA and saRNA for enhanced expression of tumor suppressor genes. Tristan Dover1, Morgan Stevens1, John Wrangle2, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University, 2Medical University of South Carolina

PS2556. Ultra-High Concentration Antibody Formulations Enabled Via Thermostable Ionic Liquids. Metecan Erdi, Ph.D.1, Anujan Ramesh, Ph.D.1, Vinny Chandran Suja, Ph.D.1, Shuyang Zhang, Ph.D.1, Samir Mitragotri, Ph.D.1, Bijay Singh, Ph.D.1 1Harvard University

PS2557. Ultrabithorax-based Biomaterials for Targeted and Triggered Release of Aromatic Drugs to Eliminate Methicillin-resistant Staphylococcus aureus (MRSA) Biofilms. Britt Faulk1 1Texas A&M University

PS2558. Optimization of Polycaprolactone Nanocapsules for In Vivo Targeted Delivery to Mouse and Human β-cells Utilizing Transplanted Murine Models. Ashton Fremin, BS MS Chemical Engineering1, August Yousse1, Alex Moore, BS Quantitative Biosciences and Engineering1, Jubril Akolade1, Nikki Farnsworth, PhD Chemical Engineering Principal Investigator1 1Colorado School of Mines

PS2559. Incorporation of Thiol-ene Microparticle into Hydrogels for Extended Antibiotic Release to Treat Osteomyelitis. Anna Rourke-Funderburg, PhD1, Chipo Chapusha1, Sheetal Chowdhury1, Amol Janorkar, PhD1 1University of Mississippi Medical Center

PS2560. Targeted Lenvatinib–PAMAM Conjugates for Precision Treatment of Triple-Negative Breast Cancer. Ritama Ghosh, WSU ID 118999071, Ananya Biswas1, Rishi Sharma1, Anjali Sharma1 1Washington State University

PS2561. Methotrexate-Loaded Transdermal Patches for Sustained Delivery in Rheumatoid Arthritis. Rahul kumar Gupta, PHD SCHOLAR1 1IIT BOMBAY

PS2562. Efficient Gelation and Prolonged Stability in Low-Polymer Thermosensitive Hydrogel. Guanzhen He1, Susan Thomas, Ph.D.1 1Georgia Institute of Technology

PS2564. Multifunctional enzyme-cleavable peptides for the delivery of small interfering RNA to ovarian tumors. Anna Kaminski, M.S.1, Kharimat Lora Alatise, PhD Bioengineering2, Chloe Jones1, Jessica Boulos, Bioengineering PhD1, Joey LaValla, BS, Bioengineering1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University, 2Eli Lilly and Company

PS2566. Novel Electrospun Fibers for Multi-Drug Delivery in Oral Cancer. A M U B Mahfuz1, Yuanyuan Duan1 1University of Mississippi Medical Center

PS2567. Nebulization of a fusion protein for SARS-CoV-2 prophylactic and treatment. Linh Mai1, Julie Champion, PhD1, Andrew Neish2, Narayanaiah Cheedarla2, Ishmamul Hoque Sadab1, Siamalan Krishnathas3 1Georgia Institute of Technology, 2Emory University, 3Georgia Insitute of Technology

PS2568. Uterotonic Delivery from a Nanoengineered Hydrogel for Intrauterine Uterine Atony Management. Tripp Moss1, Sarah Miller1, Akhilesh Gaharwar1 1Texas A&M University

PS2569. Design and Optimization of a Controlled-Release Drug Delivery System for Oral Lichen Planus Therapy. YUKINARI NAKAMURA1 1Institute of Science Tokyo

PS2570. Engineered Vaginal Ring System Enabling Controlled Cyclical Release of Ovarian Hormones. Alexander Noblett1, Brian Pham1, Akiva Gordon1, Ferran Barrachina1, Bruna Paulsen1, Christian Kramme1 1Gameto

PS2571. A Redox-Sensitive Steroid Conjugation Strategy Integrated into an MR Imaging-Active Biomaterial. Stephen Paige, B.S.1, Amber Doiron, M.S., Ph.D.1 1University of Vermont

PS2572. siRNA-LNP Driven Kinase Silencing Improves Solid Tumor Penetration and Restores Chemosensitivity in Treatment-refractory Ovarian Cancer. ShuLan Holmes-Farley, MSc1, Theresa Raimondo, PhD1 1Brown University

PS2573. Characterization of Micelle and Free Polymer Release from a Thermosensitive Hydrogel using Selective Staining. Sakthi Priya Ramamoorthy1, Maya Levitan, n.s.1 1Georgia Institute of Technology

PS2574. Leveraging cyclic peptide ligands for targeted nanoparticle drug delivery systems. Alexandra Aeschliman1, Vigneshkumar Rangasami, PhD1, Danielle Benoit1 1University of Oregon

PS2575. Polymeric Microneedle Tattoo Patch for Stress-Free Animal Identification, Performance Tracking, and Real-Time Health Monitoring. Maria J. Rey-Sanchez1, David Castilla-Casadiego, PhD1, Katherine A. Miranda-Munoz, PhD1 1University of Miami

PS2576. The Development of Thermoresponsive Tanshinone-IIa Prodrug to Accelerate the Healing of Delayed Fracture Union. Jie Rong1, Shabnam Arash1, Yangwei Deng1, Dong Wang1 1University of Nebraska Medical Center

PS2577. Understanding the Movement of NPs from Gel Environment towards Cells. Emily Rudolph, MSE1, Laura Bracaglia, PhD1 1Villanova University

PS2578. Development of an oxidation-sensitive polyanion for enhanced drug delivery from layer-by-layer films. William Spanenberg1, Karina Bruce1, Dylan Marques1, John Martin1 1University of Cincinnati

PS2579. HER2-Specific Tandem Peptides Enable Targeted Delivery of CD44 siRNA into HER2-Positive Breast Cancer. Morgan Stevens1, Audreanna Miserendino2, Tristan Dover1, Anusha Vemula1, Sevrina Tekle3, James Kalogeros, M.S Bioengineering4, Kharimat Lora Alatise, PhD Bioengineering5, Brian Booth, PhD1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University, 2UNC Eshelman School of Pharmacy, 3Spelman College, 4VitaKey Inc., 5Eli Lilly and Company

PS2580. Synthesis and Characterization of Dual pH- and ROS-responsive polymers for siRNA Delivery. Avanelle Stoltz1, Mukesh Gupta, Ph.D., Polymer Chemistry1, Nora Francini, PhD1, Megan Keech1, Craig Duvall, Ph.D., Biomedical Engineering1 1Vanderbilt University

PS2581. Effects of Polymer Type and Molecular Weight on the Preparation of Nanoparticles for Drug Delivery Applications. Trisha Sullivan, B.S1, Lauren Mehanna, PhD2, Brittany Givens, PhD1 1University of Kentucky, 2Centre College

PS2582. New Fluroquinolone Derivatives Combined with Paclitaxel against Colorectal Cancer. Elham Taherian1, Aliasger Salem, PhD2 1college of pharmacy, university of Iowa, 2University of Iowa

PS2583. hEDS Treatment: Sustained Release of Berberine at MMP-Inhibiting Concentrations from Cellulose Microparticles. Katherine Bradshaw1, Oluwaseyi Bakare1, Jessica Onyak1, Elif Ertugral2, Chandra Khothapalli2, Nic Leipzig1 1The University of Akron, 2Cleveland State University

PS2584. Purified Prodigiosin as a Natural Therapeutic Candidate: Comparative Cytotoxic Effects on Two Triple-Negative Breast Cancer Cell Lines. Adiari Vergara1, Nakelia Taylor1, Sandra Borbor-Sawyer, PhD1 1SUNY Buffalo State University

PS2585. Fructose Presentation Promotes Fructose Specific, Charge Independent, Nanoparticle Uptake In Vitro. Paige Woods, MS1, Ghaida Aldhahri1, Timothy O'Shea, PhD1 1Boston University

PS2586. Addition of Pluronic F-127 in Polycaprolactone Nano-capsules for Increased Stability in Biologically Relevant Buffers for in vitro and in vivo Applications. August Yousse1, Ashton Fremin, BS MS Chemical Engineering1, Alex Moore, BS Quantitative Biosciences and Engineering1, Nikki Farnsworth, PhD Chemical Engineering Principal Investigator1 1Colorado School of Mines

PS2587. Long-acting IGF-1 Reverses Denervation Atrophy and Restores Motor Function After Chronic Nerve Injury in Rodent and NHP Models. Yicheng Zhang, PhD1, Thomas Harris, MD PhD1, Christopher Erb, BS1, Chenhu Qiu, PhD1, Karim Serhan, MD2, Erica Lee, MD PhD2, Alexander Tinana, BS1, Moonhyung Lee, Undergrad2, Kara Segna, MD PhD2, Sashank Reddy, MD PhD2, Ahmet Höke, MD PhD2, Hai-Quan Mao, PhD1, Sami Tuffaha, MD PhD2 1Johns Hopkins University, 2Johns Hopkins University School of Medicine

PS2588. Targeted delivery of microRNA to high-risk neuroblastoma using redox-responsive polymer nanoparticles. Yu-Rim Ahn, Ph.D.1, Toola Alkhazal, B.S.2, Aming Yu, Ph.D.3, Erin Brown, M.D.2, Jinhwan Kim, Ph.D.2 1Organization* UC Davis Health, University of California, Davis, 2UC Davis Health, University of California, Davis, 3UC Davis Health,University of California, Davis

PS2589. Fluorescent and Bioluminescent Membrane Reporters Enable Accurate EV Quantification from Hydrogels: Comparison with Five Commercially Available Techniques. Hannah Aris, PhD1, Yeyu Shen, M.D.1, Garry Duffy, PhD2, Meadhbh Brennan, PhD1 1University of Galway, 2University of Galway, Royal College of Surgeons Ireland

PS2590. Development of Antimicrobial and Flame-Retardant Coating for Textiles. Evan Bauch1, Vladimir Reukov1, Quoc-Nghia Duong1, Joyjit Ghosh1, David Juhas2, Austin Van Horn2 1University of Georgia, 2Chitozan Health

PS2591. Immunomodulatory Effects of Granular Hydrogel Scaffolds for Gene Delivery. Noah Campbell1, Evan Kurt, PhD2, Tatiana Segura, PhD1 1Duke University, 2BD

PS2592. Disease-severity-responsive nanoparticles enable precise RNA delivery for osteoarthritis therapy. Mahima Dewani, PhD1, Nitin Joshi, PhD1 1Brigham and Women's Hospital

PS2593. Modulating PEGDA Molecular Weight to Balance Mechanical Integrity and Swelling in Microneedles. Danial Hosseini, M.S.1, Erkan Azizoglu, PhD1, Mark Prausnitz, PhD1 1Georgia Institute of Technology

PS2594. From Vaccines to Genome Editing: Engineering Biolistic Delivery for Dense Tissue Penetration. Shan Jiang1 1Iowa State Unviersity

PS2595. Development of Cancer-Associated Fibroblast-Derived Extracellular Vesicle-Based Gene Delivery Platform to Inhibit Peritoneal Metastasis in Gastric Cancer. Chae-lin Kim1, Hoon Hur1, Hyun-Ji Park1, Ki Dong Park1 1Ajou University

PS2596. Formulation of mRNA-LNPs into Microneedle Patches. Julie Kim1, Sophia Sakers, PhD1, B. Pradeep Reddy, PhD2, Gianna Fiduccia2, Katherine Byrne1, Ingrid Stén2, Afsane Radmand, PhD2, James Dahlman, PhD1, Mark Prausnitz, PhD2 1Georgia Institute of Technology and Emory University, 2Georgia Institute of Technology

PS2598. Development of a Dual-Adjuvant Mucosal Vaccine Formulation Utilizing a Mast Cell and TLR9 Agonist. Connor Murphy1, Grace Williamson1, Luis Ontiveros-Padilla1, Erik Pena2, Aaron Hendricksen1, Eric Bachelder1, Kristy Ainslie1 1UNC - Chapel Hill, 2NC State/UNC

PS2599. Phage‑Architecture Antibacterial Nanoparticles Clear Multidrug‑Resistant ESKAPEE Pathogens, Resensitize MDR pathogens to Legacy Antibiotics, Prevent Emergence of New MDR, and Accelerate Wound Healing. Prakash Nallathamby, Ph.D.1, Juliane Hopf, PhD1, Carlie Kudary1, Olivia Sayani, BS1, Shirley Wei, BS1, Ryan Davey, BS1, Deborah Donahue, BS1, Victoria Ploplis, PhD1, Francis Castellino, PhD1 1University of Notre Dame

PS2600. Exploring the use of Bacterial Cellulose for Biomedical Applications. Cynthia Okafor, BPharm.1, Md Meraj Anjum, PhD2, Sean M Geary, PhD2, Aliasger Salem, PhD2 1The University of Iowa, 2University of Iowa

PS2601. Advancing Brain Cancer Treatment with Biodegradable Ultrasound Transducer and Targeted Gene Therapy. Jinyoung Park, M.Sc.1, Gulsah Erel-Akbaba, Ph.D.2, Thanh Nguyen, Ph.D.1 1University of Connecticut, 2Izmir Katip Celebi University

PS2602. Engineering Milk-Derived Extracellular Vesicle–Casein Nanoparticle Hybrid Platform for Drug Delivery in Inflammatory Bowel Disease. Hye-min Park1, Hyun-Ji Park1, Ki Dong Park1 1AJou University

PS2603. Optimizing a Peptide-Based Nanoplatform for Cas9 Ribonucleoprotein (RNP) Delivery and Gene Editing. Joey LaValla, BS, Bioengineering1, Jennifer Singleton1, Alyson Schwartz, BS Bioengineering1, Audrey Wessinger, BS Bioengineering1, Santiago Rivero1, Jessica Larsen, PhD Chemical Engineering1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University

PS2605. Synergistic Dual-Nanoparticle Design for Tumor Immunotherapy and Molecular Imaging. Wei Mao1, hyuksang Yoo2 1Kangwon National University, 2Kangwon Natiional University

 

IMMUNOMODULATORY BIOMATERIALS 

PS2597. Roles of methylmalonic acid based polymers regulating immune responses in Rheumatoid Arthritis. Abhinav Acharya, PhD1, Sanmoy Pathak, PhD1, Taravat Khodaei, MS1, Madhan Mohan Chandra Sekhar Jaggarapu, PhD1 1Case Western Reserve University
 

ENGINEERING BIOMATERIALS FOR CARDIAC AND PULMONARY USES 

PS2606. 3D Printing of Mechanically Tunable Elastomers for Functional Myocardial Tissue Engineering. Narangerel Gantumur, Graduate Research Assistant1, Shanely Colon, Undergraduate Research Assistant1, Kaitlyn Vogel, Undergraduate Research Assistant1, Ying Chen, PhD, Assistant Professor1 1Rowan University

PS2607. Application Study of Extracellular Matrix Micro/Nanoparticles in Non-invasive Aerosolized Pulmonary Therapy for Acute Lung Injury in Rats. Chen-Yu Kao, Ph.D., PMP1 1National Taiwan University of Science and Technology/ Graduate Institute of Biomedical Engineering

PS2608. Optical Coherence Tomography (OCT) Evaluation of Vein Graft Adaptation Under Arterial Conditions. Bruce Gao1, Taylor Seawell1 1Clemson University

PS2609. Aligned Electrospun Piezoelectric Scaffolds for Enhancing Cardiomyocyte Maturation and Myocardial Repair. John Ryan Zimmerman1, Patrick Hwang, PhD1, Beena Baruwal1 1Rowan University

 

ENGINEERING CELLS AND THEIR MICROENVIRONMENTS SIG

PS2610. Platelet-Like Particles Modulate the Intercellular Signaling of Mesenchymal Stem Cells. Jacob Brown, PhD1, Ashley Brown, PhD1 1North Carolina State University

PS2611. β1 integrin expression identifies heterogeneities in endothelial cell vasculogenic capacity in collagen hydrogels. 

PS2612. siRNA-mediated knockdown of ITGA11 offers a therapeutic approach for vocal fold scarring. Yashna Gupta1, Ryan Friedman, PhD1, Linh Schiffer2, Riccardo Gottardi, PhD1 1University of Pennsylvania, 2DePauw University

PS2613. ꞵ1 integrin expression identifies functional heterogeneities in myoblasts for 3D engineered skeletal muscle. Keely Laurence1, James Martin1, Brian Kwee, Ph.D.1 1University of Delaware

PS2614. Enzymatically-Degradable Hydrogel Microcarriers Modulate Effects of Pro-Inflammatory Cytokine Licensing of Mesenchymal Stromal Cells. Keshav Shah, B.S., M.S.1, Johnna Temenoff2 1Georgia Tech/Emory University, 2Georgia Institute of Technology
 

EXTRACELLULAR VESICLES FOR BIOMEDICAL APPLICATIONS 

PS2615. MIAMI cells-derived extracellular vesicles (MIA-EVs) exhibit a conditioning-resistant miRNA regulatory backbone and enhanced regenerative and immunomodulatory pathways versus conventional MSC-EVs. Michelle B. R. G. Ley, University of Miami1, H. Thomas Temple, University of Miami1, Alicia R. Jackson, University of Miami1, Thomas M. Best, University of Miami1, Dimitrios Kouroupis, University of Miami1, Gianluca D’Ippolito, University of Miami1 1University of Miami

PS2616. Evaluating the Immunomodulatory Properties of Bacterial Extracellular Vesicles. Frank Borris1, Parinaz Fathi, PhD1, Kaitlyn Sadtler, PhD1, Anagha Rama Varma2 1National Institutes of Health, 2Crossroads Eye Physicians

PS2617. Evaluating the Influence of Manufacturing Parameters on Neural Extracellular Vesicles. Morgane Golan, B.S.1, Leah McCarthy, B.S.1, Kanupriya Daga, Ph.D.1, Frank Seipel, Ph.D.2, Randolph Ashton, Ph.D.2, Ross Marklein, Ph.D.1, Steven Stice, Ph.D.1 1University of Georgia, 2University of Wisconsin-Madison

PS2618. Sucrose Density Gradient Centrifugation Versus Anion Exchange for Exosome Sample Purification. Sydney Hofstetter1, Melanie Nelson1, Luis Pinzon-Hererra, Ph.D.1, Ryan Pearson, Ph.D.2, Jorge Almodovar, Ph.D.1 1University of Maryland, Baltimore County, 2University of Maryland School of Pharmacy

PS2620. Development of a Bioreactor System that Increases Cell Culture Efficiency and Facilitates Extraction of Extracellular Vesicles (EV). Daniel Nikolaev1, Vladimir Reukov1, Quoc-Nghia Duong1, Anton Murashko1 1University of Georgia

PS2621. Sphingolipid Perturbations in MSCs Mediate Increased EV Potency through Molecular Repackaging of Cargo. Daniel Shah1, S'Dravious DeVeaux2, Hongmanlin Zhang, MS3, Kejie Rui4, Afra Toma3, Steven Goudy3, Luke Mortensen4, Edward Botchwey, PhD3 1Georgia Institute of Technology and Emory Univeristy, 2Georgia Institute of Technology and Emory University, 3Georgia Institute of Technology, 4UGA

PS2622. Piezoelectrically Engineered Exosomes for Effective Cell-Free Muscle Repair. Breanne Welsh1, Prabaha Sikder1 1Cleveland State University

 

FAILURES, PIVOTS AND SURPRISES 

PS2623. Confinement and Restricted Protein Transport Regulate Cell Viability in Poly(Ethylene Glycol) Hydrogels. Nathan Richbourg, Ph.D.1, Akaansha Rampal, Ph.D.2, Adrian Lorenzana, Ph.D.2, Shelly Peyton, Ph.D.3 1FAMU-FSU College of Engineering, 2UMass Amherst, 3Tufts University

PS2624. Why do ultrafine fibrous hydrogels release drugs more slowly than standard hydrogels?. Shiqi wei1, Fiona Peterson1, Fiona Feng1, Blair Brettmann1 1Georgia Institute of Technology
 

FIBROUS BIOMATERIALS FOR TISSUE ENGINEERING 

PS2625. Character and Formulation of Fibrinogen Cross-Linked by FXIII and/or FXIIIa. Jun Adan-Kubo, Ph.D., MBA1 1Japan Blood Products Organization

PS2626. Evaluation of Cell Viability on Fibrous Poly (lactic acid) Scaffolds for Skin Tissue Engineering. Marziyeh Boosaliki, PhD student1, Mahtab Khodadadi, PhD student2, Yaala Smith3, Martin King, PhD2, Jessica Gluck, PhD2 1Wilson College of Textile North Carolina State University, 2NC State University, 3Wilson College of Textiles, North Carolina State University

PS2627. Metallic Nanoparticle-Enhanced Fibrous Scaffolds for Pro-Regenerative Skin Repair and Wound Healing. Dekonti Davies, B.S, M.S.1, Narayan Bhattarai, PhD2 1North Carolina A & T State University, 2NCAT

PS2628. Exploring Various Fabrication Techniques of Hemp as Sustainable Alternatives in Biomaterials. Kaleah Gaddy1, Jessica Gluck, PhD2 1North Carolina State University, 2NC State University

PS2629. Bioengineered Polycaprolactone/Gelatin Nanofiber-Gelatin Methacryloyl Composite Hydrogels for Enhanced Cardiomyocyte Maturation. Mahtab Khodadadi, PhD student1, Martin King, PhD1, Jessica Gluck, PhD1 1NC State University

PS2630. Polyester electrospun patches provide effective hemorrhage control. Prathamesh Mane1, Abraham Joy, N/A1 1Northeastern University

PS2631. Enhanced Wound Healing Performance of Electrospun PCL-Zinc Scaffolds Functionalized with Fibroblast-Derived Extracellular Matrix. Narayan Bhattarai, PhD1, Alexis Moody, M.S.1 1NCAT

PS2632. Ring-Opening Polymerization of Ambrettolide: A Path to Nanofiber-Based Tendon Scaffolds. Robert Silzer1, Nicola Judge, PhD2, Matthew Becker, PhD1 1Duke University, 2Duke Univeristy

PS2633. Development and Characterization of Surface-Modified Electrospun Polyurethane Tubular Scaffolds for Functional Renal Proximal Tubule Constructs. ANJALI SUDHA1, Amrita Natarajan1, Kyra A Ramirez1, Vineeth M vijayan1, Derrick Dean1 1Alabama State University

PS2634. Modulating an Injectable Fibrin Scaffold to Increase Satellite Cell Viability and Survival. Isabel Wallgren, BS, BA1, Oliver Deng2, Jared Albert3, Ashley Brown, PhD3, Laura Hansen2 1Emory University & Georgia Tech, 2Emory University, 3North Carolina State University
 

GRANULAR & MICROPOROUS BIOMATERIALS FOR TISSUE ENGINEERING 

PS2635. Determining the Biomaterial-Mediated Mechanism of Cell Migration in Heterogeneous Heparin-Containing Scaffolds. Juliana Trujillo1, Don Griffin, Ph.D.1 1University of Virginia

PS2636. Reactive-Oxygen-Species-Degradable Polysulfide Foams. Paolo Francisco1, Mukesh Gupta, Ph.D., Polymer Chemistry1, Craig Duvall, Ph.D., Biomedical Engineering1 1Vanderbilt University

PS2637. Post-Droplet Deformation into Polyhedral Microgels for 3D Porous Scaffold Formation. Yoke Qi Ho1, Sasha Cai Lesher-Pérez2 1University of Michigan, 2University of Michigan-- Ann Arbor

PS2638. Tunable Hydrolytically Degradable Polyethylene Glycol-based Granular Hydrogels for Targeted Stem Cell Delivery. Eferoghene Okakuro, MS1, Mykel Green, Ph.D.1 1Tulane University

PS2639. Buoyancy-Cleared Microfluidic Encapsulation of Bacterial, Mammalian, and Multicellular Systems in PEG Microgels. Wahidur Rahman1, Gabriela Garza1, Bradley Biggs1, Aaron Morris1, Sasha Cai Lesher-Pérez1 1University of Michigan-- Ann Arbor

PS2640. Injectable Silogel Sponges for Rapid Hemostasis. Pritha Sarkar1, Kausik Mukhopadhyay, PhD1 1University of Central Florida

PS2641. FGF18-Conjugated Zwitterionic Annealed Microgels Enhance Stem Cell Proliferation and Chondrogenesis. Erika Wheeler1, J. Kent Leach1 1UC Davis Health

 

CARDIOVASCULAR BIOMATERIALS SIG

PS264. Development of a Polymeric Coating for Inhibition of Blood Component Adhesion on Sensors. Sandy Gomes1, Estela Baldin1, Gabriela Freitas1, Eduarda Paglia1, Susan Jorge1, Hernandes Carvalho1, Mariana Moraes1, Marisa Beppu1 1University of Campinas

PS2643. 3D Printed Radiopaque Bioresorbable Citrate-based Cardiovascular Scaffolds. Shivakalyani Adepu, Doctorate1, Alexandra DeFilippis1, Bianca Navarro1, Reyhan Civ1, Cheng Sun1, Guillermo Ameer1 1Northwestern University

PS2644. Influence of Postprocessing on Elastin-Like-Recombinamer Based Biohybrid Vascular Implants. Dominic Andre1, Alexander Loewen1, Svenja Deichmann1, Nicole Schaaps1, Stephan Ruetten2, José Carlos Rodríguez-Cabello3, Stefan Jockenhoevel1, Thomas Schmitz-Rode1, Alicia Fernández-Colino1 1RWTH Aachen University, 2Uniklinik, RWTH Aachen University, 3Bioforge Lab, Universidad de Valladolid

PS2645. Design of a Durable Hydrogel Coating to Improve Tissue Contact in Radiofrequency Ablation. Derek Bashe1, Archita Duvvada1, Octavio Jalife1, Bhanaviya Venkat1, Mathews John2, Drew Bernard2, Lukas Jaworski2, Mehdi Razavi, MD2, Allison Post, PhD2, Elizabeth Cosgriff-Hernandez, Ph.D.1 1University of Texas at Austin, 2Texas Heart Institute

PS2646. UPI Peptide Delivery via Microparticles to Promote Vascular Graft Endothelialization. Chris Bashur, PhD1, Fatemeh Goodarzinia1, Shirin Changizi, PhD1, Sunita George, MS1, Cyrah Pinnock1, Hong Chen, PhD2 1Florida Institute of Technology, 2Harvard Medical School

PS2647. Effects of Aliphatic Diisocyanates on Self-Doped Conductive Biodegradable Polyurethanes. Huikang Fu1, Jiazhu Xu, PhD1, Yufeng Wen1, Zining Yang1, Yi Hong, PhD1 1The University of Texas at Arlington

PS2648. Elastin-Targeted PGG-BSA Nanoparticles for Abdominal Aortic Aneurysm Reversal. David Madukwe, MSc1, Naren Vyavahare, PhD1 1Clemson University

PS2649. Targeted Therapeutics to Modulate Myeloid-Derived Innate Immune Cell Phenotype. Abigail McSweeny1, Shreya Soni1, Arielle D'Elia1, Kenneth Kim2, Christopher Rodell, Ph.D.1 1Drexel University, 2Drexel University College of Medicine

 

3D BIOPRINTING FOR DEVELOPING PERSONALIZED MODELS

PS2650. Integrating Precise Heat Control For Open-Source Bioprinting Using Chocolate As A Temperature-Sensitive Material. Amanda Mejia1, Cody Crosby1 1Southwestern University

FRIDAY, March 27

POSTER SESSION III: BIOMATERIALS AFTER HOURS SOCIETY HANGOUT: INSPIRE & IMAGINE 
4:30 PM - 6:00 PM 

 

CARDIOVASCULAR BIOMATERILAS SIG 

PS3500. An Improved Manufacturing Method for Infusible Extracellular Matrix Materials to Enable Investigation of Tissue Specific Effects and Future Clinical Translation. Michael Nguyen, PhD1, Emma Zelus, PhD1, Colin Luo, MS1, Carlos Munoz, MS1, Pedro Cabrales, PhD1, Karen Christman, PhD1 1University of California, San Diego

PS3501. Engineering a Coil-Reinforced Multilayer Vascular Graft to Balance Compliance and Kink Resistance. Mabel Prejean1, Andrew Robinson1, David Jiang, Ph.D.2, Abbey Nkansah1, Jonathan Lueng3, Madeline Laude4, Lucas Timmins, PhD5, Abdou Elgalad, MD, PhD6, Elizabeth Cosgriff-Hernandez, Ph.D.4, Juan Herrera1, John Craig1, Leopold Guo1, Xiaoxiao Zhang7 1University of Texas, 2Medtronic Neurovascular, 3Department of Biomedical Engineering, University of Texas at Austin, 4University of Texas at Austin, 5Texas A&M University, 6Center for Preclinical Surgical & Interventional Research, 7Texas Heart Institute

PS3502. Development of affinity-based delivery systems for exploring the impact of temporally regulated VEGF, FGF-2, and PDGF delivery on angiogenesis. Justin Svendsen, Student1, Chandler Asnes, B.S.1, Samuel Nightheart, B.S.1, Armaan Hajarizadeh, N/A1, Madeleine Ford, B.S.1, Simon Oh, B.S.1, Parisa Hosseinzadeh, Ph.D.1, Robert Guldberg1, Marian Hettiaratchi, Ph.D.2 1University of Oregon, 2University of Oregon Knight Campus

PS3503. Zn-releasing electrospun polyurethane fiber reduced hypoxia-ischemia/reperfusion injury in H9c2 cells. Yufeng Wen1, Yingjie Liu, PhD2, Tristan Pyle3, Huikang Fu4, Shengqian Ma, PhD, Professor3, Zui Pan, PhD, Professor2, Yi Hong, PhD4 1University of Texas, 2University of Texas at Arlington, 3University of North Texas, 4The University of Texas at Arlington

PS3504. Coaxial Dry-Jet Wet Spinning of Tunable Hollow-Fiber Vascular Scaffolds. Libin Yang1, Xiao Sun1, James Jaraczewski1, Kenan Song1 1University of Georgia

PS3505. Photomodification of bioprosthetic heart valves with Vitamin B6 to mitigate structural valve degeneration. Andrey Zakharchenko, PhD1, Nikia Toomey, M.D.1, Ivan Alferiev, PhD1, Alexis Martinez1, Oksana Horyn1, Devin Laurence, PhD1, Alireza Mohammad Karim, PhD1, Arianna Adamo, PhD2, Stanley Stachelek, PhD1, Giovanni Ferrari, PhD2, Robert Levy, M.D.1 1The Children's Hospital of Philadelphia, 2Columbia University

PS3663. Multilayer Vascular Grafts with Integrin Targeting for Sustained Thromboresistance. Ashauntee Fairley1, Abbey Nkansah1, Nicolai Ang1, Maddie Laude1, Andrew Robinson, Ph.D1, Nicholas Grammer1, Elizabeth Cosgriff-Hernandez, Ph.D.1 1University of Texas at Austin

 

HIGH PERFORMANCE BIOMATERIALS FOR TISSUE ENGINEERING AND REGENERATIVE MEDICINE 

PS3506. Resilient Semi-Interpenetrating Polymer Network Emulsion Hydrogels for Soft Tissue Bulking Applications. Meghan Halloran1, David Alpert2, Adam Weisel1, Diana Kirke, MD3, Steven Nicoll, Ph.D.1, Kelly Garrett, MD4 1CUNY City College of New York, 2The CIty College of New York, 3Mount Sinai Hospital / Icahn School of Medicine at Mount Sinai, 4Weill Cornell Medicine

PS3507. Development of a Biomimetic ECM Blend of Hyaluronic Acid and Recombinant Collagen for Regenerative Medicine. Gabriele Pitingolo1, Lixin Dai2, Monique de Leeuw3, Anne-Laure GAUDRY1 1HTL Biotech, 2HTL Bioinnovation Inc, 3Bioinnovation Inc

PS3508. Fabrication of a Novel Hybrid and Multifunctional Scaffold for Volumetric Bone Regeneration. Rana Ibrahim1, Nicole Petrocelli1, Matangi PR1, Maya Lapinski1, Hongjun Wang1 1Stevens Institute of Technology

PS3509. Integrated Development of Biodegradable Polymer Stents with Prescribed Mechanical Behavior. Kenan Song1, Libin Yang1, James Jaraczewski1, Fatemeh Mahdavi1, Zhengfu Huang1, Manlilang Luo1 1University of Georgia

PS3656. Hyaluronic Acid-Based Hydrogel Containing Graphene Quantum Dot–Polydeoxyribonucleotide Nanocomposites for Photothermal and Antioxidant Diabetic Wound Therapy. Yun-Ha Cho1, Min-Ho Kang1 1The Catholic University of Korea

PS3664. Localized treatment of metastatic bone cancer via MXene enhanced scaffolds paired with TTFs. Aleyna La Croix1, Emma Kerimo1, Sreejith Panicker2, jewelia Durant1, Tatum Saunders1, Neva Nemanic1, Anand Tiwari, PhD3, Will Scheideler, PhD1, Katherine Hixon1 1Dartmouth College, 2Washington University in St. Louis, 3University of South Florida

 

IMMUNE ENGINEERING SIG 

PS3510. Biomechanical changes in the aging inguinal lymph node. Suh Hee Cook, PhD1, Katharina Maisel, PhD1 1University of Maryland

PS3511. Molecularly Engineered Dynamic Hydrogels with Covalent Adaptability for Mechanically Tunable and Responsive Gasotransmitter. Natalie Crutchfield1, Martin Sobczak1, Arpita Shome, Ph.D.1, Shermane Sylvester1, Kenan Song1, Elizabeth Brisbois, Ph.D.1, Hitesh Handa, Ph.D.1 1University of Georgia

PS3512. Interleukin-2 Regulation of Human T-cell Phenotypes. Nathan Gonsalves, M.Sc.1, Lohitash Karumbaiah, Ph.D.1 1University of Georgia

PS3513. Evaluating the Effects of Mitochondrial Transplantation on Neutrophils In Vitro for Host-Biomaterial Integration. Samantha Hall, M.S.1, Evan Main, M.S.1, Gary Bowlin, Ph.D.1 1The University of Memphis

PS3514. Improving Ex Vivo Lymph Node Slice Cultures by Application of Fluid Flow. Yoojin Lee, PhD1, Tiffany Tran, B.S.1, Sara Dombroski1, Simona Bajgai1, Hannah Musgrove, PhD1, Lavoisier Akoolo, PhD2, Melanie Rutkowski, PhD1, Rebecca Pompano, PhD1 1University of Virginia, 2UVA Health

PS3515. Nanoparticle-mediated targeting of the innate immune cell receptor, CLEC12A, on dendritic cells. Samantha Singer, B.S.1, Marian Ackun-Farmmer, PhD1 1Georgia Institute of Technology

PS3516. Calcium-modulating microparticles for influencing Vomocytosis from Macrophages. Daniel Stafstrom, B.S.1, Jamal Lewis, Ph.D.1 1University of Florida

PS3517. Human tissue-derived membrane for the prevention of surgical adhesions. Shu Tang, Phd1, Nitisha Mehrotra2, Crystal Shin, Ph.D1, Ghanshyam Acharya, Ph.D1 1Baylor College of Medicine, 2Rice University

PS3518. Phosphate Cross-linked Polyvinyl Alcohol (PxPVA) as inflammation-modulating biopolymer. Men Tran1, Nitisha Mehrotra2, Ghanshyam Acharya, Ph.D1, Crystal Shin, Ph.D1 1Baylor College of Medicine, 2Rice University

PS3519. Selenium-Functionalized Heparin for Combined Catalytic, Antibacterial, and Anticoagulant Activity on Nitric Oxide-Releasing Surfaces. Annalise Tucker, PhD1, Elizabeth Brisbois, Ph.D.1, Mark Garren, Ph.D.1, Hitesh Handa, Ph.D.1 1University of Georgia

PS3520. Engineered Immunological Niche Remotely Captures Immune Dynamics of Cardiac Allograft Vasculopathy. Bryan Wonski, PhD1, Russell Urie, PhD1, Kyla Zhao1, Shannon Dame1, Jiane Feng, MD, PhD1, Evan Farkash, MD, PhD1, Lonnie Shea1 1University of Michigan

PS3521. A Recombinant S1P Chaperone Protein Limits Inflammation and Fibrosis After Volumetric Muscle Loss. Hongmanlin Zhang, MS1, Lauren Hymel, PhD1, Jeehyun Lee, PhD1, Stanislav Emelianov, PhD1, Nick Willett, PhD2, Young Jang, PhD3, Timothy Hla, PhD4, Edward Botchwey, PhD1 1Georgia Institute of Technology, 2University of Oregon, 3Emory University School of Medicine, 4Harvard Medical School

 

IMMUNOMODULATORY BIOMATERIALS 

PS3522. Homopolymeric and chimeric, gut-inspired immunosuppressive microparticles cause immunosuppression of bone-marrow-derived dendritic cells. Reuben Abraham1, Krishna Gaddam1, Allen B Tu1, Jamal Lewis, Ph.D.1 1University of Florida

PS3523. Trophoblast-mediated tolerance in Type 1 Diabetes autoimmunity. Ariana Belton1, David Pardo1 1Arizona State University

PS3524. Hydrogel Encapsulated FTY720P-Licensed MSC as a Potential Therapeutic For ONF. Babatunde Giwa-Otusajo1 1Geaorgia Tech

PS3525. Engineering Immunological Niche for Monitoring Anti-CD3 Treatment Efficacy in Type 1 Diabetes. Brianna Ha1, Jyotirmoy Roy1, Lonnie Shea1 1University of Michigan

PS3526. Engineering Human FRC-Based Reticula for Antigen-Specific Tolerance Induction in Type 1 Diabetes. Lucy Ho, BS1, Leonor Teles, BS1, Mira Sayegh1, Logan Beatty, BS2, Camillo Bechi Genzano, MD3, Remi Creusot, PhD3, Alice Tomei4 1University of Miami, 2Harvard-MIT, 3Columbia Center for Translational Immunology, 4University of Miami, Diabetes Research Institute

PS3527. Silk-Derived Sericin Modulates Inflammatory and Barrier-Related Pathways in Keratinocytes and Fibroblasts: Toward a Natural Therapeutic Strategy for Atopic Dermatitis. Jan Jurak1, Łukasz Mazurek1, Mateusz Rybka1, Anna Laskowska1, Szymon Salagierski2, Michał Dziadek2, María del Mar Ribas Taberner3, Antonio Sureda3, Marek Konop1 1Medical University of Warsaw, 2AGH University of Krakow, 3University of the Balearic Islands

PS3528. Immunoprotection of Transplanted Allogeneic Islets Through Local Drug Delivering, 3D-printed Scaffolds. Taylor Lansberry, BS1, Robert Accolla, Ph.D.2, Cameron Crouse, B.S.1, Irayme Labrada Miravet, BS1, Cherie Stabler, Ph.D.1 1University of Florida, 2Humacyte

PS3529. Kynurenine Production Evaluation by a therapeutic protein, galectin-anchored indoleamine 2,3-dioxygenase (IDO-Gal3). Chen Lu1 1University of Flordia

PS3530. Immunosuppressive anti-CD3 Microgels Protect Transplanted Insulin-Producing Beta Cells in Type 1 Diabetes. Cameron Manson1, Adrienne Widener1, Jessie Barra1, Amanda Grodman1, Andrew Ladd1, Holger Russ1, Edward Phelps1 1University of Florida

PS3531. IL-33-releasing hydrogels for treating ischemic muscle injuries. Lauren Mottel, M.S.1, Brennagh Shields, M.S.1, Lindsay Gallagher1, Brian Kwee, Ph.D.1 1University of Delaware

PS3532. XCR1+ Conventional Dendritic Cell Dynamics and Modulation with Indoleamine 2-3, Dioxygenase in Liver Ischemia-Reperfusion Injury. Tran Ngo1, Jennifer Simonovich, PhD1, Ali Zarrinpar, MD, PhD1, Benjamin Keselowsky, PhD1 1University of Florida

PS3533. Engineering Covalently Crosslinked Peptide-Oligonucleotide Complexes for Stable Immune Signal Delivery. Yugma Patel1, Marian Ackun-Farmmer, PhD1 1Georgia Institute of Technology

PS3534. Effects of Localized ABT-263 on Aged Murine Bone Marrow Macrophages. Govindaraj Perumal, Postdoc1, Travis Wallace-Ferrara, Ph.D.1, Rachael Norris, Ph.D.1, Liisa Kuhn, Professor1 1University of Connecticut Health

PS3535. PEGylation of Stimulator Cells Results in Dampened T cell Activation of Responder Cells at Early Time Points. Damea Pham1, Cherie Stabler, Ph.D.1, Allison Bayer, Ph.D.1 1University of Florida

PS3536. Mesaconate delivering probiotic reduce inflammation in Crohn's disease. Huikang Qian1 1Case Western Reserve University

PS3537. Controlled baricitinib release from hydrogels through reversible thioimidate bonds to treat autoimmune skin diseases. Leo Wang, MD, PhD, FAAD1, George Cotsarelis, MD1 1University of Pennsylvania

PS3538. Hierarchically Porous Microgel Scaffolds for Immune Modulation and Tissue Regeneration. Yunqian Zhang1, Ni Su1, Jay Patel1 1University of Kentucky

PS3539. A Heterotetramer of Galectin-1 and Galectin-3 Mitigates Localized Sterile Inflammation. Zhuo Chen1, Megan Sanders1, Jennifer Simonovich, PhD1, Benjamin Keselowsky, PhD1, Gregory Hudalla, PhD1 1University of Florida

 

MANUFACTURING AND TRANSLATION OF POLYMER-BASED IMPLANTS, FIBROUS INTERFACES AND TISSUE ENGINEERING SCAFFOLDS 

PS3540. Nanofiber-Integrated Food Packaging: Combining Transparency, Antibiofilm Functionality, and Spoilage Detection. Burhan Ates1, Ashish Trital1, Sarah Fakher1, Edmunt Palermo2, Ryan Gilbert1 1Missouri University of Science and Technology, 2Rensselaer Polytechnic Institute

PS3541. Zn-Integrated Fibrous Scaffold Promotes Neovascularization Through a Paracrine Effect. Sita Shrestha, Ph.D.1, Salil Desai, Ph.D.1, Narayan Bhattarai, PhD2 1North Carolina A&T State University, 2NCAT

PS3542. Colorimetric Infection Detection Using Electrospun Chitosan Membrane Wound Dressings. Onyinyechukwu Okoli1, Sumiran Sharma1, Ebla Bogoneh1, Benjamin Agyemang1, David Hunt1, Jermiah Tate1, J. Amber Jennings, PhD1 1The University of Memphis

PS3543. 3D Printable Hydrogel as a Tissue Scaffold for Pelvic Organ Prolapse Treatment. James Jaraczewski1, Libin Yang1, Manlilang Luo1, Zhengfu Huang1, Kenan Song1 1University of Georgia

PS3544. Investigating the Impact of Synthetic Scaffold Architecture on Fibronectin Fibrillogenesis. Eleanor Plaster1, Seongjun Moon, Ph.D.1, Joerg Lahann, Ph.D.1 1University of Michigan

PS3545. Aerosol-jet Printed Flexible Graphene Sensor for Chronic Wound Biomarker Monitoring. Md Salauddin Sk, Msc1, Azrin Jamison, Msc1, Benjamin Schwartz, Undergraduate junior1, Sydney Demers, Undergraduate senior1, Logan Rush, Undergraduate junior1, Jordon Gilmore, PhD1 1Clemson University

PS3546. The effect of propolis addition on the physicochemical properties of electrospun polycaprolactone nonwovens. Janusz Szewczenko1, Zuzanna Warska1, Tymon Warski2, Andrzej Hudecki2, Hanna Spałek2, Anna Gawron3 1Silesian University of Technology, 2Łukasiewicz Research Network, 3Polish Academy of Sciences

PS3547. Development and Characterization of PCL/PLGA Core-Shell Electrospun Fibers for Guided Tissue Regeneration Applications. Lohitha Kalluri1, A M U B Mahfuz2, Yuanyuan Duan2, Varish Varakantam3 1Nova Southeastern University, 2University of Mississippi Medical Center, 3Georgia Institute of Technology

PS3548. A solution to electrospinning complex solutions: The effect of hydrogen-bond valence. Shiqi wei1, Gyubin Kim1, Nora O'Kelly1, Yvonne Walker1, Blair Brettmann1 1Georgia Institute of Technology

PS3550. Melt Electro-writing of PCL-based Polyurethane Heart Valves with Multi-material, Multilayered, and Multicomponent Architectures for Personalized Cardiovascular Support. Libin Yang1, Kenan Song1 1University of Georgia
 

NANOMATERIALS IN HEALTH & DISEASE 

PS3551. TiO2 Nanohelices Decorated with Homogeneous Au-Core Pd-Shell Nanocatalysts for Selective Toluene Gas Detection. Hanseo Bae, Ph.D. in progress1, Hyeonwoong Hwang, Ph.D. in progress1, Sei Kwang Hahn, Ph.D.1 1Pohang University of Science and Technology

PS3552. Wireless, Battery Free Self-detecting Smart graft for Stenosis Diagnosis in AV Grafts for Dialysis Patients. Allison Bateman1, Woon-Hong Yeo, PhD1 1Georgia Tech

PS3553. Characterization of Temozolomide Nanoparticles for Glioblastoma Treatment: A Comparison of Synthesis Protocols. Victoria Blanc, BS1, Alyssa Callahan1, Nicholas Brunelli, PhD1, Aleksander Skardal, PhD1, Katelyn Swindle-Reilly, PhD1 1The Ohio State University

PS3554. Targeted Therapeutics for Head and Neck Cancer Produced by Scalable Fabrication Methods. Tristan Cole1 1Missouri University of Science and Technology

PS3555. SILVERED SERS Nanosubstrates for Ultrasensitive Detection of Alzheimer's Disease Biomarkers in Extracellular Vesicles. Farbod Ebrahimi1 1JSNN

PS3556. Dextran-DOTA Macromolecular Nanoconjugates for Safer Systemic Heavy Metal Removal. Sebastian Guajardo1, Hunter Wood1, Chenyun Deng1, Stefanie Sydlik1 1Carnegie Mellon University

PS3557. Real-time Monitoring of Protein Corona Formation on Polymer Dots Using Fluorescence Resonance Energy Transfer Spectroscopy. Kushani Mendis, Ph.D. Candidate1, Zeev Rosenzweig, Ph.D.1 1University of Maryland Baltimore County

PS3558. Laser induced graphene transdermal heating patch for thermal treatment of biofilm. Collin Richards1, Prakriti Dhungana1, Byung-Wook Park1 1Youngstown State University

PS3559. Multimodal Sensitivity Enhancement of Immunoassays using Functional PEG Hydrogels. Pranshu Rajurkar, MS1, Samantha Wise2, Aniruddh Sarkar, Ph.D.1 1Georgia Tech and Emory University, 2Georgia Institute of Technology

PS3560. Green Microfluidic Synthesis Of Silver Nanoparticles And Their Antimicrobial Activity Against Bacteria And Fungi. Magdalena Antonowicz-Hüpsch1, Lenka Klecandova2, Gabriela Kratosova2, Alicja Kazek-Kęsik3, Grazyna Simha Martynkova2 1Silesian University of Technology/Faculty of Biomedical Engineering, 2VŠB - Technical University of Ostrava, 3Silesian University of Technology

PS3561. Surface Chemistry-Dependent Protein Corona Formation on Poly(amido)amine Dendrimers to Inform Endothelial‑Targeted Cardiovascular Nanomedicine Design. Deborah Wood1, Surya Murali2, Simone Douglas-Green, Ph.D.1 1Georgia Institute of Technology & Emory University, 2Georgia Institute of Technology

PS3562. Characterization of Protein Coronas on Dendrimer-Lipid Nanoparticles. Lesley Gutierrez1, Colten Hall2, Sydney Dobler2, Rasheed Adigun, Ph.D.2, Briana Simms, Ph.D.2, Simone Douglas-Green, Ph.D.1 1Georgia Institute of Technology & Emory University, 2University of Cincinnati

PS3563. Synthesis & Evaluation of Drug-Loaded Composite Nanoparticles for Anti-Cancer Treatment. Morgan McArthur, M.S.1, Cheryl Gomillion, Ph. D.1 1University of Georgia

PS3564. EVNaturopatch: A Stable and Safe Approach for the Delivery of Phenylpropanoids for theTargeted Modulation of Inflammation-Driven Pain. Naomi Thomas1, Yahya N Najjar2, Katherine Warpeha2, Divya Rani Bijukumar1 1University of Illinois, College of Medicine, Rockford, 2University of Illinois Chicago

PS3565. Comparative Evaluation of Ultrasound-Triggered Controlled Release of Curcumin from Electrospun Nanofibrous Mesh for Wound Healing Applications. Joshua Wilkins1, Abhijith Sreejith1, Milani Needam1, Langston Hill1, Sita Shrestha, Ph.D.1, Muna Aryal, Ph.D.1, Narayan Bhattarai, PhD2 1North Carolina A&T State University, 2NCAT

PS3566. Health-Relevant Nanocomposite Membranes: Ag/MWCNT-COOH Modified Hollow Fibers for biofouling Control and Enhanced Transport. Vikash Kumar1, Jayesh Bellare2 1IIT Bombay, 2Indian Institute of Technology Bombay

 

OPHTHALMIC BIOMATERIALS SIG 

PS3567. Advancing Long-Acting AMD Therapy: Structure–Performance Relationships and a Data-Driven Optimization Framework for Thermoresponsive Hydrogels. Alexa Beathard-Wojan1, Vibhuti Agrahari, Ph.D.1 1University of Oklahoma Health Campus

PS3568. Mucin Depletion Induces Changes in the Contact Mechanics of the Corneal Epithelial Glycocalyx and the Inflammatory Response of Corneal Epithelial Cells to Friction. Nemea Courelli1, Ahmed Al Kindi1, Angela Pitenis, PhD1 1University of California, Santa Barbara

PS3570. Amoxapine-Loaded Gel Eyedrops for a Hormonal Approach to Dry-Eye Disease. Poulami Ghosh1, Peter Jansen1, Issac Reynaga1, Katelyn Swindle-Reilly, PhD1 1The Ohio State University

PS3571. Solid Drug Nanoparticle Embedded Thermosensitive Hydrogel Eye Drop for Enhanced Glaucoma Management. Lei Xu1, Tzu-Chen Wang2, Shichu Chang3, Lin Qi2, Vimalin Jeyalatha Mani2, Bohong Zhang1, Jie Huang1, Xiaorong Liu3, Hu Yang4, Ned Kronenberg3 1Missouri University of Science and Technology, 2Marquette University and the Medical College of Wisconsin, 3University of Virginia, 4Marquette University and Medical College of Wisconsin

PS3572. Electrospun Poly (lactide-co-glycolic acid) Fibrous Scaffolds: Modification and Characterization for Corneal Wound Healing in Veterinary Applications. Anna Asadi, DVM, PhD Student1, Marziyeh Boosaliki, PhD student2, Nasif Mahmood3, Brian C. Gilger, DVM, PhD3, Jessica Gluck, PhD4 1North Carolina State University, 2Wilson College of Textile North Carolina State University, 3College of Veterinary Medicine, North Carolina State University, 4NC State University

PS3573. An Insulin-like Growth Factor-1 Sustained Release Strategy Preserves Retinal Tissue and Function in a Mouse Model of Retinal Degeneration. Sophia Lu, BHSc1, Jonathan Labriola, PhD1, Margaret Ho, PhD2, Harry Chin, BASc1, Hong Cui, PhD1, Diane Lee1, Lacrimioara Comanita, BSc3, Valerie Wallace, PhD3, Molly Shoichet, PhD, FRSC, NAE, O Ont, FRS1 1University of Toronto, 2Broad Institute of MIT and Harvard, 3Toronto Western Hospital/University Health Network

 

ORTHOPAEDIC BIOMATERIALS SIG 

PS3574. Development of a Delivery Method for Human Subacromial Bursa Tissue Using Alginate-Based Hydrogels. Peyton Hadfield1, Stefan Minyayluk2, Mary Beth McCarthy2, Augustus Mazzocca, MD2, Joseph DeAngelis, MD1, Benjamin Freedman, PhD1 1Beth Israel Deaconess Medical Center / Harvard Medical School, 2Mass General Brigham

PS3575. Magnesium-Based Nanocomposites for Bone Repair and Osteoimmunomodulation through Effects on Osteogenesis and the Inflammatory Environment. Samantha Gmitro, M.S.1, Andres Alayon Mata2, Andres Larraza1, Mishfak Abdullah Mansoor1, Michal Masternak, PhD1, Mehdi Razavi, PhD2 1University of Central Florida College of Medicine, 2University of Central Florida, College of Medicine

PS3576. Effect of Chlorine dioxide terminal sterilization on Simplex P bone cement with Tobramycin. Shulin He1, Qing-Qing Qiu2, Dermot Reeves1, Maurice OConnell1, Brinda Badwe1 1Stryker Co, 2Stryker Orthopedics

PS3578. Manganese Dioxide Nanoparticles Doped β-tricalcium Phosphate (β-TCP) Scaffolds Protect Cells and Enhance Osteogenesis. Yunqing Kang1 1Florida Atlantic University

PS3579. Does Electrocautery Damage Correlate with Tribological Wear and Metal Ion Concentration in Surrounding Periprosthetic Tissue in Retrieved CoCrMo Femoral Condyles?. Nathan Lopus1, Peter Kurtz1, Shabnam Aslani2, Michael Kurtz3, Lilliana Taylor1, Emma Barnes3, Daniel MacDonald3, Nicolas Piuzzi4, William Mihalko5, Steven Kurtz3, Jeremy Gilbert, Ph.D.6 1Clemson-MUSC, 2Drexel University Implant Research Core, 3DUIRC, 4Cleveland Clinic, 5Campbell Clinic, 6Clemson University

PS3580. Immunomodulatory potential of HMGB1 in diabetic microenvironment for orthopedic applications. Danieli Rodrigues, PhD1, Claudia Biguetti, DDS, MSc, PhD2, Jimena Mora3 1University of Texas at Dallas, 2University of Texas at Rio Grande Valley, 3The university of Texas at Dallas

PS3581. Impact of Sterilization Modalities on 3-D Printed Nylon-12 Medical Devices. Behrooz Nasseri-Aghbosh1, Qing-Qing Qiu1 1Stryker Orthopedics

PS3582. Biodegradable Poly(caprolactone)/Poly(silyl fumarate) Shape Memory Scaffolds. Jenlyan Negron Hernandez1, Kaley Beach1, Paola Chavarria1, Melissa Grunlan, Ph.D.1 1Texas A&M University

PS3583. Radiation Dose-Dependent Effects on Cryogel Scaffold Integrity and Cytocompatibility. Georgia Nieh1, Peter Bertone1, Katherine Hixon1 1Dartmouth College

PS3584. Development of a hybrid surface modification tailored to the specificity of highly porous, AM metallic orthopedic implants, providing properties beneficial for short- and long-term biological response. Ada Orłowska1, Janusz Szewczenko2 1Silesian University of Technology/Faculty of Biomedical Engineering, 2Silesian University of Technology

PS3585. Hybrid PEO/P(L/G/TMC) Coatings as a Strategy to Control the Degradation of Magnesium Alloys for Orthopedic Applications. Barbara Rynkus1, Maciej Sowa1, Ada Orłowska2, Karolina Wilk1, Joanna Jaworska3, Katarzyna Nowińska1, Janusz Szewczenko1 1Silesian University of Technology, 2Silesian University of Technology/Faculty of Biomedical Engineering, 3Polish Academy of Sciences

PS3586. Antibacterial Properties of Modified Carrageenan Polyelectrolyte Multilayer Surfaces. Aniruddha Vijay Savargaonkar1, Isaac Njoku1, Liszt Madruga2, Ketul Popat2, Matt Kipper1 1Colorado State University, 2George Mason University

PS3587. A Collagen-Binding Fusion Protein for Localized Bone Morphogenetic Protein-2 (BMP-2) Delivery from Collagen. Malvika Singhal, BS1, Marian Hettiaratchi, Ph.D.2 1University of Oregon/Knight Campus, 2University of Oregon Knight Campus

PS3588. Osteogenic capacity of octacalcium phosphate bone substitute controlled by MSC migration with chemokine. Osamu Suzuki1, Yu Mori2, Ryo Hamai1, Ryuichi Kanabuchi2, Yasuaki Kuriyama2, Kaori Tsuchiya1, Toshimi Aizawa2 1Tohoku University Graduate School of Dentistry, 2Tohoku University Graduate School of Medicine

PS3589. A structurally reinforced biomimetic nanocomposite scaffold for ligament regeneration. Pooyan Vahidi Pashaki, Ph.d.1, Dr. Dinesh Katti, Ph.d.1, Dr. Kalpana Katti, Ph.d1 1NDSU

PS3590. Design of Hydroxyapatite Whisker Reinforced Polyetheretherketone Scaffolds for Bone In-Growth and Mechanical Integrity in Orthopedic Devices. Luis Vega Lugo1, Gannon Becker1, Nikola Jovanovic1, Owen Holsinger1, Zachary Roeder1, Hezekiah Williams1, Ryan Roeder, PhD1 1University of Notre Dame

PS3592. Effect of suture size, number of throws, and loading condition on polyvinylidene suture failure: An in vitro study. Katrijn Whisenant, DVM, DACVS-LA1, Pierre-Yves Mulon, DVM, DES, DACVS-LA1 1University of Tennessee College of Veterinary Medicine

PS3593. Fabrication of Piezoelectric Nanofiber Scaffolds and Their Application to Biomaterial for Tissue Engineering. Yoon Seong Choi1, Jang Ho Park1, Tae Woo Lee1, Kyeongwoon Chung1, Jong Pil Yoon2, Ho Yun Chung2, Sula Han3, Jin-Hyun Choi1 1Kyungpook National University, 2Kyungpook National University Hospital, 3SOFNT

 

PEPTIDE BIOMATERIALS FOR THERAPEUTIC APPLICATIONS 

PS3594. The Characterization of CASP Hydrogels for the Delivery of TMZ and siRNA to Treat Glioblastoma. Aaron Anderson1, Jessica Boulos, Bioengineering PhD1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University

PS3595. A Peptide-Based Nanoplatform for Cas9 Ribonucleoprotein Delivery and Gene Editing to Treat Glioblastoma​. Jada Goff, B.S. in Biomedical Engineering1, Joey LaValla, BS, Bioengineering1, Jennifer Singleton1, Santiago Rivero1, James Whitten1, Jessica Larsen, PhD Chemical Engineering1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University

PS3596. Characterization of the GE11-599-siRNA Delivery System for a Locally Administered Co-Loaded Hydrogel to Treat Glioblastoma. Daphne Gomez Escudero1, Jessica Boulos, Bioengineering PhD1, Angela Alexander-Bryant, PhD Bioengineering1, Kay Russi1, Emalee Mann1, Aaron Anderson1 1Clemson University

PS3597. pH-Responsive supramolecular nanoparticles as targeted drug delivery systems. Ricardo Pires1, Mara Costa1, Vânia Castro1, Ana Rita Araújo1, Sílvia Lima1, Rui Reis1 1University of Minho

PS3598. Comparison of Cas9 Delivery Using Non-Viral Vectors. Santiago Rivero1, Joseph LaValla1, Jennifer Singleton1, Angela Alexander-Bryant, PhD Bioengineering1, Jayda Goff1, Jessica Larsen, PhD Chemical Engineering1, Michael Mitchell, PhD2, Hannah Yamagata3 1Clemson University, 2University of Pennsylvania, 3UPenn
 

SEX, AGE AND EQUITY AS BIOLOGICAL VARIABLES IN BIOMATERIALS RESEARCH 

PS3599. Effects of Microgravity on Endometrial Cells in Gelatin Methacryloyl Hydrogels. Keshav Bhandari1, Cristina Bonilla1, Norah Masri1, Samantha Zambuto1 1University of Kentucky

PS3600. Engineering Estrogen: Granulosa Cell Encapsulation in Granular Hydrogels for Hormone Restoration Studies. Natasha Claxton, Ph.D.1, Arielle Efotte, M.S.1, Jay Huber, M.D., Ph.D.2, Lindsay Wells, M.D.3, Mykel Green, Ph.D.1 1Tulane University, 2The Fertility Institute of New Orleans, 3Audubon Fertility

PS3601. Development and Validation of an Endometriosis Model for High-Throughput Phenotypic Screening. Del Donehoo1, Ines Cadena, PhD1, Emma Piccione1, Molly Jenne1, Kaitlin Fogg, Dr.1 1Oregon State University

PS3602. A Vascularized Human Placenta-on-a-Chip for Modeling Maternal–Fetal Crosstalk and Environmental Exposure. Pouria Fattahi, Ph.D.1 1University of Georgia

PS3603. Metabolic Variations of Triple-Negative Breast Cancer and Polymersome-Mediated RNAi Therapy. Matthew Harrington, BS1, Alannah Akins1, James Whitten1, Heather Dunn, BS, MS, Ph.D., Postdoc1 1Clemson University

PS3605. Cleavable Tandem Peptides for Targeting Genes Associated with Chemoresistance in Ovarian Cancer. Jason Schrader1, Amanda Murray2, Anna Kaminski, M.S.1, Mira Patel1, Alejandra Rodriguez1, Angela Alexander-Bryant, PhD Bioengineering1, Kharimat Alatise3, Ruxi Xia4 1Clemson University, 2University of Pennsylvania, 3Eli Lilly and Company, 4Columbia University

PS3606. Developing an ovarian-specific hydrogel model for the in vitro study of endometrioma. Hannah Theriault1, Rene Mohammadi1, Sia Mittal1, Kathryn Clancy1, Brendan Harley1 1University of Illinois at Urbana Champaign

PS3607. Developing a 3D in vitro model investigating endometrioma-ovarian perivascular crosstalk. Hannah Theriault1, Sia Mittal1, Rene Mohammadi1, Katie Karecki1, Kathryn Clancy1, Brendan Harley1 1University of Illinois at Urbana Champaign

PS3608. SDF-1α loaded bioadhesives for early intervention of pelvic organ prolapse. Zining Yang1, Alan Taylor2, Tam nguyen2, Luis Soto-Garcia2, Jiazhu Xu, PhD1, Jun Liao2, Philippe Zimmern3, Liping Tang2, Kytai Nguyen2, Yi Hong, PhD1 1The University of Texas at Arlington, 2University of Texas at Arlington, 3University of Texas Southwestern

 

BIOMATERIALS INNOVATIONS FOR WOMEN’S HEALTH 

PS3604. Optimizing Human Uterine Tissue Processing for Precursor Gel Formulation. Zelalem Ayalew1, Elena Wegner2, Guillermo Ameer2, Taneka Jones, PhD1 1Lehigh University, 2Northwestern University
 

STIMULI-RESPONSIVE BIOMATERIALS 

PS3609. Electro-osmotic Bioactive Pumps Promote Lymphatic Drainage and Regeneration for Lymphedema Treatment. Shivesh Anand, PhD1, Ande Marini, PhD1, Tatiana Zaitseva, PhD2, Michael Paukshto, PhD2, Dung Nguyen, MD, PharmD1, Ngan Huang, PhD1 1Stanford University, 2Fibralign Corporation

PS3610. Microwave-Assisted Synthesis of Water-stable Phosphonium-bismuth Halide Semiconductors with Photo-selective Antifungal Activity. Alissa Anderson1, Ioannis Spanopoulos1 1University of South Florida

PS3611. Shape Memory Hydrogel Implants for Minimally Invasive Encapsulated Cell Therapy. Benjamin Wilson, B.S.1, Sudip Chakraborty1, Adelmo Lopez, M.S.1, Suman Bose, Ph.D.1 1Mayo Clinic

PS3612. Dual Light and pH Responsive Core–Shell Microparticles for Chemo-Photothermal Cancer Therapy. Ali Salifu, PhD1, Tom Buckman, BS1, Lillian Serpe, BS1, Maria Chinyerem Onyekanne, PhD1 1BOSTON COLLEGE

PS3613. Off-the-Shelf Medical Adhesives from α-Lipoic Acid and Its Derivatives. Hannah Chen1, Subhajit Pal, PhD1, Phillip Messersmith, PhD1 1UC Berkeley

PS3614. Development of Degradable Granular Hydrogels for Tissue Engineering Applications. Zhiyuan Chen1, Taimoor Qazi1 1Purdue University

PS3615. Photoresponsive Gold Nanoparticle-Loaded Polymersomes for Controlled Cargo Release and Intracellular Delivery under Pulsed Laser Irradiation. Julianne Griepenburg1, Regina Salzer1, Sebastian Zmijewski, CT(ASCP)1, Ajay Shah1, Cory Trout1, Eric Klein1, Sean O'Malley1 1Rutgers University-Camden

PS3616. Intracellular Degradable Cationic Microgel for miRNA Delivery. Akifumi Kawamura1, Akari Umemoto1, Shun Fujisawa1, Yosuke Inomata2, Kohei Taniguchi2, Takashi Miyata1 1Kansai University, 2Osaka Medical and Phermaceutical University

PS3617. Zwitterionic Peptide Tags to Guide the Nanoarchitecture of Elastin-Like Polypeptides. Kat Lazar1, Yulia Shmidov, PhD1, Judy Lee1, Neel Dutta Gupta1, Joel Collier, PhD1, Ashutosh Chilkoti, PhD2 1Duke University, 2Duke

PS3618. Improved Thermoplastic Polyurethane Foams With Sequential Shape Memory for Pediatric Implantation. Matthew Lesko, MS, Graduate Assistant1, Mary Beth Monroe2, James Henderson, PhD, Professor1 1Syracuse University, 2Texas A&M University

PS3619. Conducting Polymer Nanoparticles for On‑Demand, Low‑Voltage Drug Release. Olivia Dossias1, Cheyane Nichols1, Elia Bllani1, Ian Anderson, B.Sc.2, Solaleh Miar, PhD1 1University of Hartford, 2WPI

PS3620. The Supercell: a step towards developing active and autonomous materials. Tia Monjure1, Thomas Angelini, PhD1, VIgnesh Subramaniam, PhD1 1University of Florida

PS3621. Mesenchymal Stem Cell-Inspired Microneedle Platform for NIR-responsive Immunomodulation and Accelerated Chronic Wound Healing. Chan Ho Moon, B.S. Candidate1, Hee Gyeong Ko, M.S.2, Han Young Kim, Ph.D.2, Hyun-Do Jung, Ph.D.1 1Hanyang University, 2The Catholic University of Korea

PS3622. Visible Light-Responsive Photosoftening Hydrogels for Modeling Dynamic Tissue Mechanics in Tissue Remodeling. Golnaz Navidi1, Ben Canter1, Ella Morris1, Teresa Rapp, PhD1 1University of Oregon

PS3623. Bio-Enabled Sensing Technologies. Jessica Semel, Master's1, Isabell Bradshaw, Master's1, Mark Gasser, D. Eng.1, Olayide Ashiru, Master's1, Marina Gonzalez1, Denise Hoover1, Thomas Lawton, PhD1, Elizabeth Robinson, PhD1 1JHU/APL

 

TISSUE ENGINEERING SIG 

PS3624. PEG-functionalized TGF-β1 engages SMAD2/3 signaling in human pulmonary fibroblasts. Samuel Agro, B.S.1, Lakeshia Taite, Ph.D.1 1University of Virginia

PS3625. Functionalized Cellulosic Polymer Network Hydrogels for Soft Tissue Reconstruction. Jesse Martin, Ph.D.1, David Alpert1, Adam Weisel1, Meghan Halloran1, Steven Nicoll, Ph.D.1 1CUNY City College of New York

PS3626. Fabrication and Characterization of Silk-Derived Actuators. Anik Banerji1 1St. John's School

PS3627. Real-Time 3D Non-invasive Bioimpedance Monitoring of Cellular Remodeling, Vascular Network Formation, and Native Tissue Differentiation. Chih-Ling Chang1, Ying-Chieh Chen1 1National Tsing-Hua University

PS3628. Bioprinting of Patient-derived Ovarian Cancer Organoids with Vascularization for Drug Screening Applications. Zhenhua Cui1, Min Wang1 1The University of Hong Kong

PS3630. Porosity of Microporous Annealed Particle (MAP) Scaffolds modulates cell behavior. Clare Flanagan1, Don Griffin, Ph.D.1 1University of Virginia

PS3631. Dynamic Peptide–ZnDPA Coordination Enables On-Demand RGD Functionalization of 3D Printable Alginate Hydrogels. Rananjaya Gamage, PhD1, Hai Pham1, Daniel Montes Pinzon1, Bradley Smith, PhD1, Donny Hanjaya-Putra, PhD1 1University of Notre Dame

PS3632. Designing a Growth Plate Organoid Model with a Proliferative Zone to Inhibit Hypertrophy. Elizabeth George, MA1, Stephanie Bryant, PhD2 1University of Colorado Boulder, 2Univeristy of Colorado - Boulder

PS3633. Volumetrically Printed Autograft‑Bone‑Containing Hydrogel Lattices for Improved Clinical Usability. Patrick Hall1, Julia Andraca Harrer, BS, MS, PhD2, Maya Kasteleiner1, Strata Kim, B.S2, Kait Link, DVM2, Gabriella Lindberg, PhD1, Nick Willett, PhD2, Paul Dalton, PhD2 1Knight Campus, University of Oregon, 2University of Oregon

PS3634. Assembly of Large Engineered Cardiac Tissues within Poly(Ethylene Glycol) Fibrinogen Using Stem Cell-Laden Microsphere Building Blocks Undergoing Cardiac Differentiation. B Justin Harvell1, Mohammadjafar Hashemi1, Della A Kelly1, Kevin D Roehm, PhD2, Balabhaskar Prabhakarpandian, PhD3, Elizabeth Lipke, PhD1 1Auburn University, 2CFD Research Corporation, 3CFD Research Company

PS3635. Simulated Microgravity as a Platform for Screening Drugs that Promote Myogenesis in Engineered Muscle. Beu Oropeza, PhD1, Ngan Huang, PhD2 1Veterans Affairs Palo Alto Health Care System, 2Stanford University

PS3636. Comparison of Spheroids and Organoids on Three Basement Membrane Extracts for Use in a Thyroid-on-a-Chip. Parnika Kant1, Anagha Rama Varma2, Paniz Rezvan Sangsari1, Nicole Morgan, PhD1, Kaitlyn Sadtler, PhD3, Parinaz Fathi, PhD3 1National Institute of Biomedical Imaging and Bioengineering, 2Crossroads Eye Physicians, 3National Institutes of Health

PS3637. Enhancing Mesenchymal Stem Cell Therapy for Wound Healing by Inhibiting Anoikis with Carboxymethyl Cellulose-Polylactic Acid Particles. Dong-Hyun Lee1, You Bin Lee1, Suk Ho Bhang1 1Sungkyunkwan University

PS3638. Establishing Uniform and Spatially Patterned Transfection with Nanopore Electroporation. Emily McCorkle1, Matthew Manion1, Xiaoqian Wang1, Cheyenne Meeks1, Guanren Tao1, Albert Liu1, Sasha Cai Lesher-Pérez2 1University of Michigan, 2University of Michigan-- Ann Arbor

PS3640. Endothelialized Sacrificial Alginate Microfibers for Rapid Graft Microvascularization. Firaol Midekssa1, Maggie Jewett1, Elizabeth Stanely1, Kaylin Hanna1, Vanini Pimpalwar1, Brendon M. Baker, PhD2 1University of Michigan, 2UNIVERSITY OF MICHIGAN- ANN ARBOR

PS3642. Tuning Granular Hydrogels Matrix Composition to Support Lymphatic Capillaries Formation in vitro and in vivo. Daniel Montes Pinzon1, Angela Taglione1, Ellie Johandes1, Salmady Ramos Valentin1, Donghyun Jeong1, Hsueh-Chia Chang1, Donny Hanjaya-Putra1 1University of Notre Dame

PS3643. Stratum Corneum on a Quartz Crystal Microbalance Sensor (Organ on a Chip): Real-time Monitoring of the Adsorption of Topical Drugs onto Skin. Dilek Gelen-Gungor1, Hana Mohd2, Ipek Eroglu1, Bozena Michniak-Kohn2, N. Sanjeeva Murthy2 1Hacettepe University, 2Rutgers University

PS3644. Evaluating the Effects of Annealing Mechanism on Microporous Annealed Particle Scaffold Integration for Glottic Insufficiency. Ethan Nicklow1, Don Griffin, Ph.D.1, James Daniero1 1University of Virginia

PS3645. PIEZO1 in Mechanosensation of Stiffness and Regulation of Muscle Fibro-Adipogenic Progenitors. Kasoorelope Oguntuyo1, Charlene Cai1, Larion Santiago1, Woojin Han1 1Icahn School of Medicine at Mount Sinai

PS3646. Hyperosmotic Pressure Mimics Mechanical Confinement and Regulate Muscle Stem Cell Fate. GaYoung Park1, Josh Grey2, Woojin Han1 1Icahn School of Medicine at Mount Sinai, 2Icahn School of Medicien at Mount Sinai

PS3647. Photoactivatable Dual-Function CRISPRa/i Platform for Spatiotemporal Gene Regulation in 4D. Oumsri Raghavendran Priya1, Cole Deforest, PhD1 1University of Washington

PS3648. Composite Scaffolds of Polylactic Acid, Apatite, and BMP-2-Laden GelMA Microparticles for Bone Regeneration. Kathryn Chang, Undergraduate1, Tom Buckman, BS1, Ali Salifu, PhD1 1BOSTON COLLEGE

PS3649. Enhancing Ischemic Muscle Repair with Amphiregulin-Releasing Alginate Hydrogels. Brennagh Shields, M.S.1, Lauren Mottel, M.S.1, Lindsay Gallagher1, Caroline LaSalle1, Brian Kwee, Ph.D.1 1University of Delaware

PS3650. 3D Engineered Heart Tissues Derived from Patient hiPSCs Reveal Reduced Cardiomyocyte Population and Functional Impairment in Hypoplastic Left Heart Syndrome. Shireen Singh1, Elizabeth Lipke, PhD1 1Auburn University

PS3651. Replicating BME-like Stress Relaxation in a Synthetic Matrix Sustains Liver Organoid Phenotype. Ahmed Usaid1, Oluwaseyi Bakare1, Nic Leipzig1 1The University of Akron

PS3652. Clinically desired small-diameter blood vessels for limb salvage:  The ostrich carotid artery-derived acellular blood vessel with 2mm ID. Tetsuji Yamaoka1, Atsusi MAHARA2, Koh OGAWA3, Hiroki YAMANAKA3, Naoki MORIMOTO3 1Komatsu University, 2National Cerebral and Cardiovascular Center Research Institute, 3Kyoto University

PS3653. A Bone-on-a-Chip Platform to Recapitulate the Osteoid Mechanical Microenvironment under Osteoporotic Conditions using an In Situ Biomineralizable Hydrogel with Tandem Dynamic Crosslinking. Boguang Yang1, Shangsi Chen1, liangbin Zhou1, Rocky Tuan1, Zhong Alan Li1 1The Chinese University of Hong Kong

PS3654. Nanofibrous Hydrogel-Mediated S1PR3 Modulation Improves Muscle Repair After Volumetric Muscle Loss. Hongmanlin Zhang, MS1, Lauren Hymel, PhD1, Nick Willett, PhD2, Young Jang, PhD3, Edward Botchwey, PhD1 1Georgia Institute of Technology, 2University of Oregon, 3Emory University School of Medicine

PS3662. Mechanical Performance of a PLGA Spacer Fabric–Integrated Osteochondral Repair Scaffold. Yusuf Dikici, PhD1, Kamal Gautam, MS1, Alan Shepardson, BS1, Maximilian Zernic, BS1, Linda Ohrn, PhD2, Clare Rimnac, PhD1, Ozan Akkus, PhD1 1Case Western Reserve University, 2Kent State University

 

COMPUTATIONAL, MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE APPROACHES IN BIOMATERIALS 

PS3655. ProCAST: A Visualization Tool for Analyzing Protein Coronas and Nanoparticle Behaviors. Huyju Mun1, Maxwell Leamy2, Anika Kaushik2, Christopher Kieslich, Ph.D.3, Simone Douglas-Green, Ph.D.3 1Georgia Tech and Emory University, 2Georgia Institute of Technology, 3Georgia Institute of Technology & Emory University

PS3659. Modeling the influence of cell morphology on tissue mechanical anisotropy via finite element analysis of a soft composite material with ellipsoidal inclusions. Julian Rey, PhD1, Peter Basser, PhD1 1National Institutes of Health

 

ADVANCING ANTIMICROBIAL BIOINTERFACES: ADDRESSING IMPLANTABLE DEVICE-RELATED INFECTIONS  

PS3658. Effect of 13-93-B3 Borate Bioactive Glass Incorporated Poly (methyl methacrylate) Bone Cement on Bacterial Viability in Agitated and Static Conditions. Rylie Parr, Bachelors of Science1, Rebekah Blatt, Bachelors of Science2, Richard Brow, PhD2, terence McIff, PhD3 1The University of Kansas Medical Center, The University of Kansas, 2University of Missouri Science and Technology, 3University of Kansas

PS3660. Thermoresponsive Gallium Liquid Metal Nanoparticle Hydrogels for On-Demand Eradication of Chronic Ear and Bone Infections. Vi Khanh Truong1, Ngoc Huu Nguyen1 1Flinders University

 

BIOMATERIAL-BASED CANCER MODELS 

PS3661. 3D Tissue-Engineered Lung Cancer Models Reveal Fibroblast-Dependent Microenvironmental Remodeling. Elham Seyyedi Zadeh1, Kwaghtaver Desongu1, Adam Lee2, Weijie Zhang2, yuan Tian1, R. Stephanie Huang2, Elizabeth Lipke1 1Auburn University, 2University of Minnesota

 

BIOMATERIALS AND NANOTECHNOLOGY FOR CANCER MODELING AND THERANOTICS 

PS3665. Supramolecular Injectable Hydrogel with Drug-Loaded MXene for Near-Infrared Photothermal Chemotherapy. Seung Min Yang, Ph.D. in progress1, Hyunsik Choi, Ph.D.1, Sei Kwang Hahn, Ph.D.1 1Pohang University of Science and Technology

PS3669. Three-Dimensional Spheroids as In Vitro Models of the Tumor Microenvironment for Glioblastoma Treatment. Emalee Mann1, Jessica Boulos, Bioengineering PhD1, Aaron Anderson1, Sylvanie Johnson, Bachelor of Science2, Megan Pitz, PhD in Bioengineering1, Angela Alexander-Bryant, PhD Bioengineering1 1Clemson University, 2Emory University

 

ANTIMICROBIAL AND ANTIBIOFILM BIOINTERFACES: STRATEGIES TO PREVENT DEVICE-ASSOCIATED INFECTIONS 

PS3666. NIR-infrared responsive hydrogenated TiO2 nanoscale honeycomb surface pattern for rapid S. aureus biofilm elimination and enhanced osteogenesis. Yizhou Zhu1, Kelvin Yeung1 1The University of Hong Kong
 

MODEL SYSTEMS FOR EVALUATION OF DRUG DELIVERY BIOMATERIALS 

PS3668. Biomaterial-Enabled Localized Immunomodulation: Acute In Vitro and In Vivo Auto- and Allo-Immune Response Models. Ana Hernandez, BS1, Chris Li2, Peter Buchwald3, Alice Tomei4, Dhanashree Surve5 1University of Miami Miller School of Medicine, 2Unviersity of Miami, 3Diabetes Research Institute, University of Miami, 4University of Miami, Diabetes Research Institute, 5University of Miami