7H: Biomaterials for In Vitro Models of Disease 2
Time: 8:00 AM to 10:00 AM
Description
This session is dedicated to biomaterials used in the fabrication of in vitro disease models and will highlight cutting-edge strategies for replicating pathological conditions outside the human body. Topics will include the use of biomaterials in the development of organoids, microphysiological systems, and hydrogels for 3D cell culture. The session will explore their applications in studying disease mechanisms, drug testing, and recent advancements in leveraging these platforms for personalized medicine and therapeutic development.
Moderators:
Silviya Zustiak, Ph.D
Professor and Associate Chair; Co-Director, Institute of Drug and Biotherapeutic Innovation at SLU
Biomedical Engineering
Professor of Pharmacology and Physiology
Saint Louis University
Kyle Lampe
Associate Professor, Chemical EngineeringAssociate Professor, Biomedical Engineering and Neuroscience
The University of Virginia
8:00 AM. 397. Engineered Immune Organoid–on–Chip Platform Reveals Chemokine Receptor Dysregulation Impairs Germinal Center Organization in Lymphoma Patients.Manuel Quiñones-Pérez1, Zhe Zhong1, Jean Koff2, Ankur Singh1 1Georgia Institute of Technology, 2Emory School of Medicine, Emory University
8:15 AM. 398. Engineered Colorectal Cancer Tissue Model in Obesity-linked Insulin-Resistant Microenvironment for Mechanistic Investigation of Disease Progression.Kwaghtaver Desongu1, Ifeoluwa Odeniyi, PhD1, Callie Pope, Student1, Peter Peter Abraham, B.Sc1, Grace Hester, B.Sc1, Michael . Greene, PhD1, Elizabeth Lipke1 1Auburn University
8:30 AM. 399. Tunable Magnetorheological Elastomer Substrates for Studying Mechano-Genetic Interactions in Hypertrophic Cardiomyopathy.Yasaman Kargar Gaz Kooh1, Yuwen Sun1, Bahareh Bahman1, Ganesh Malayath1, Leah Hayem1, Debeni Devi Nongmaithem1, Guy Genin1, Nathaniel Huebsch1 1Washington University in St. Louis
8:45 AM. 400. Comparative Transcriptomic Analysis of a 3D PEG-based Lung Tumor Model to Subcutaneous Xenograft.Suzanne Lightsey1, Heather Kates, PhD1, Kalyanee Shirlekar, PhD1, Jason Brant, PhD1, Blanka Sharma, PhD1 1University of Florida
9:00 AM. 401. Compressive Bioreactor Enables Evaluation of Anti-Inflammatory Drug Responses in Young and Aged Donor-Derived Mesenchymal Stromal Cells.Thai Thanh Hoang1, Katherine Griffin1, Sabrina Mierswa1, J. Kent Leach1 1UC Davis Health
9:15 AM. 402. Engineering Focal Cardiac Fibrosis Models via Digital Light Processing of Hydrogel Molds.Jason Burdick, Ph.D.1, Mackenzie Obenreder, B.S. Biomedical Engineering, Boston University1, Arianna McCarty1 1University of Colorado Boulder
9:30 AM. 396. Talk by Melissa Kemp, Georgia Institute of Technology