1:45 PM. 181. Small Molecule Tethered Silicone Biomaterials Surfaces Controlling Microbial Infection by Interfering with Nucleotide Second Messenger Signalling.Gaurav Pandey1, Parya Akram2, Christopher Siedlecki3, Li-Chong Xu3 1Pennsylvania State University, 2Penn State Harrisburg, 3Penn State College of Medicine